- 当前位置：首页 > >Merck Millipore > 生命科学研究
- 生命科学研究
- 产品介绍
描述 概述 Recombinant, human GSK-3β fused at the N-terminus to a His•Tag® sequence and expressed in E. coli. A dual specificity kinase that plays important roles in insulin- and Wnt-mediated cellular signalings. In AD (Alzheimer’s disease), GSK3β has a major role in microtubule stability by its ability to phosphorylate the microtubule associated protein tau. Its known substrates include glycogen synthase, p90rsk, Tau, c-Jun, and CREB. MW: 53,000-56,000. 产品目录编号 361524 品牌系列 Calbiochem®
同义词 GSK-3β, Tau Protein Kinase I, TPK I 参考 参考 Harwood, A., and Braga, V.M. 2003. Nat. Cell Biol. 5, 275.
Bhat, R.V., and Budd, S.L. 2002. Neurosignals 11, 251.产品信息 形式 Solid 配方 Lyophilized from 0.1 M NH₄CO₃. 生物信息 生物活性 1 µg GSK-3β maximally phosphorylates 100 ng Tau protein in 30 min in an in vitro kinase assay at 30°C, pH 7.5 纯度 ≥90% by SDS-PAGE 理化信息 溶解度 PBS 储存和货运信息 货运代码 Dry Ice Only
毒性 Standard Handling
储存 ≤ -70°C
无需冷冻 No
特殊指南 Following reconstitution aliquot and freeze (-70°C). Stock solutions are stable for up to 3 months at -70°C.
上一件merck millipore产品：merck millipore,默克密理博,539251,Protein A, Alkaline Phosphatase Conjugate
下一件merck millipore产品：merck millipore,默克密理博,04-419,Anti-phospho-Rsk1 (Thr359/Ser363) Antibody, rabbit monoclonal
相关产品
merck millipore,默克密理博,LSK2ABG60,Montage离心柱与 PROSEP-G 介质
merck millipore,默克密理博,ABE495,Anti-KDM1B Antibody
merck millipore,默克密理博,SF-3005,CRK; Human, Cyanine 3 RNA Detection Probe,SmartFlare
merck millipore,默克密理博,539251,Protein A, Alkaline Phosphatase Conjugate
merck millipore,默克密理博,04-419,Anti-phospho-Rsk1 (Thr359/Ser363) Antibody, rabbit monoclonal
merck millipore,默克密理博,AB2953,Anti-ATG3 Antibody
merck millipore,默克密理博,IP02,Protein A Agarose Suspension
merck millipore,默克密理博,512533,MKLP-2 Inhibitor, Paprotrain - Calbiochem
