• merck millipore,默克密理博,324800,Epoxomicin, Synthetic - Calbiochem
  • merck millipore,默克密理博,324800,Epoxomicin, Synthetic - Calbiochem

    产品名称:Epoxomicin, Synthetic - Calbiochem
    产品型号:324800
    An antitumor and anti-inflammatory agent that acts as a potent, highly specific, and irreversible inhibitor of chymotrypsin-like (CT-L), trypsin-like (T-L), and peptidyl-glutamyl peptide hydrolyzing ( More>>

    merck millipore,默克密理博,324800,Epoxomicin, Synthetic - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,324800,Epoxomicin, Synthetic - Calbiochem

    重要规格表

    经验配方
    C₂₈H₅₀N₄O₇
    描述
    概述 An antitumor and anti-inflammatory agent that acts as a potent, highly specific, and irreversible inhibitor of chymotrypsin-like (CT-L), trypsin-like (T-L), and peptidyl-glutamyl peptide hydrolyzing (PGPH) activities of the proteasome. Modifies the proteasomal catalytic subunits LMP-7, MECL1, and Z. Does not affect the activities of non-proteasomal proteases such as trypsin, cathepsin B, or chymotrypsin. A 1 mM (50 µg/90 µl) solution of Epoxomicin, Synthetic (Cat. No. 324801) in DMSO is also available.
    产品目录编号 324800
    品牌系列 Calbiochem®
    同义词 Proteasome Inhibitor XIV
    参考
    参考 Meng, L., et al. 1999. Proc. Natl. Acad. Sci. USA 96, 10403.
    Sin, N., et al. 1999. Bioorg. Med. Chem. Lett. 9, 2283.
    Hanada, M., et al. 1992. J. Antibiot. 45, 1746.
    产品信息
    具有ATP竞争性 N
    形式 White solid
    Hill配方 C₂₈H₅₀N₄O₇
    化学配方 C₂₈H₅₀N₄O₇
    Molar Mass 554.7
    可逆 N
    结构配方图像
    生物信息
    主靶 CT-L,T-L,PGPH activity of proteasome
    纯度 ≥95% by HPLC
    理化信息
    细胞可渗透 N
    溶解度 DMSO or MeOH
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 -20°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
    加拿大出口规定 Due to the country and/or U.S. state of origin of the animal material used in this product, this product may not be exported to Canada.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,324800,Epoxomicin, Synthetic - Calbiochem

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