merck millipore,默克密理愽
  • merck millipore,默克密理博,FCMAB135F,Milli-Mark Anti-BMP-7-FITC Antibody, clone 2A10

  • merck millipore,默克密理博,FCMAB135F,Milli-Mark Anti-BMP-7-FITC Antibody, clone 2A10

    产品名称：Milli-Mark Anti-BMP-7-FITC Antibody, clone 2A10
    产品型号：FCMAB135F
    Detect BMP-7 using this Milli-Mark Anti-BMP-7-FITC Antibody, clone 2A10 validated for use in FC.

    merck millipore,默克密理博,FCMAB135F,Milli-Mark Anti-BMP-7-FITC Antibody, clone 2A10

  • 产品介绍
  • merck millipore,默克密理博,FCMAB135F,Milli-Mark Anti-BMP-7-FITC Antibody, clone 2A10

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    HFCMFITCMonoclonal Antibody
    描述
    产品目录编号 FCMAB135F
    商名
    • Milli-Mark
    描述 Milli-Mark Anti-BMP-7-FITC Antibody, clone 2A10
    Alternate Names
    • osteogenic protein-1
    • Bone morphogenetic protein-7
    背景信息 Bone morphogenetic protein-7 (BMP-7), also known as osteogenic protein-1, is a member of the TGF- superfamily, and is widely expressed during embryonic development. Like other members of the bone morphogenetic protein family, BMP-7 works synergistically with BMP-2 to play a key role in the differentiation of mesenchymal cells into bone and cartilage tissues by actively recruiting stem cells from the surrounding tissue, thereby initiating the bone formation cascade. In adult cells, BMP-7 is predominately expressed in the brain, kidneys, and bladder.
    产品信息
    格式 FITC
    控制
    • HeLa cells.
    演示 Purified mouse monoclonal IgG1κ conjugated to FITC in PBS with 0.1% sodium azide and 15 mg/mL BSA.
    应用
    应用 Detect BMP-7 using this Milli-Mark Anti-BMP-7-FITC Antibody, clone 2A10 validated for use in FC.
    主要应用
    • Flow Cytometry
    应用说明
    Working Solution Cells / test Total Reaction Volume
    5 μl 5 x 105 Cells / 95 μl PBS 100 μl
    10 μl 1 x 106 Cells / 90 μl PBS 100 μl
    生物信息
    免疫原品种 Recombinant full-length BMP-7 protein.
    表位 Unknown
    克隆 2A10
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Mouse
    特异性 This monoclonal antibody recognizes BMP-7.
    同种型 IgG1κ
    品种反应性 Human
    Species Reactivity Note Tested and passed on Human. Unconjugated antibody (MAB4350) also reacts against Mouse.
    抗体类型 Monoclonal Antibody
    Entrez基因编号
    • NP_001710.1
    基因符号
    • OP1
    • BMP7
    纯化方法 Protein G purfied
    UniProt编号
    • P18075
    UniProt汇总 Function Induces cartilage and bone formation. May be the osteoinductive factor responsible for the phenomenon of epithelial osteogenesis. Plays a role in calcium regulation and bone homeostasis.

    Subunit structure Homodimer; disulfide-linked. Interacts with SOSTDC1. Interacts with TWSG1 By similarity.

    Subcellular location Secreted.

    Tissue specificity Expressed in the kidneys and bladder. Lower levels seen in the brain.

    Post-translational modification Several N-termini starting at positions 293, 300, 315 and 316 have been identified by direct sequencing resulting in secretion of different mature forms (Ref.5).

    Pharmaceutical use Available under the names Osigraft (Stryker). Its use is indicated in the treatment of tibial non-union of at least 9 month duration, secondary to trauma, in skeletally mature patients, in cases where autograft has failed or is unfeasible.

    Sequence similarities Belongs to the TGF-beta family.
    产品使用声明
    质量保证 Evaluated by flow cytometry using HeLa cells.
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Stable for 1 year at 2-8°C from date of receipt.
    包装信息
    数量 100 tests

    merck millipore,默克密理博,FCMAB135F,Milli-Mark Anti-BMP-7-FITC Antibody, clone 2A10

上一件merck millipore产品：merck millipore,默克密理博,341597,FGF-II, Mouse, Recombinant, E. coli
下一件merck millipore产品：merck millipore,默克密理博,324800,Epoxomicin, Synthetic - Calbiochem


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