merck millipore,默克密理愽
  • merck millipore,默克密理博,MAB1935,Anti-Fibronectin Antibody, CT, clone 868A11

  • merck millipore,默克密理博,MAB1935,Anti-Fibronectin Antibody, CT, clone 868A11

    产品名称：Anti-Fibronectin Antibody, CT, clone 868A11
    产品型号：MAB1935
    This Anti-Fibronectin Antibody, C-terminus, clone 868A11 is validated for use in ELISA, WB for the detection of Fibronectin.

    merck millipore,默克密理博,MAB1935,Anti-Fibronectin Antibody, CT, clone 868A11

  • 产品介绍
  • merck millipore,默克密理博,MAB1935,Anti-Fibronectin Antibody, CT, clone 868A11

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    HWB, ELISAMPurifiedMonoclonal Antibody
    描述
    产品目录编号 MAB1935
    品牌系列 Chemicon®
    商名
    • Chemicon
    描述 Anti-Fibronectin Antibody, CT, clone 868A11
    产品信息
    格式 Purified
    演示 In 0.02MPB with 0.25M NaCl, pH=7.6 with 0.1% Sodium azide.
    应用
    应用 This Anti-Fibronectin Antibody, C-terminus, clone 868A11 is validated for use in ELISA, WB for the detection of Fibronectin.
    主要应用
    • Western Blotting
    • ELISA
    应用说明 ELISA

    Immunohistochemistry, formalin fixed, 10-25 μg/ml

    Western blotting at 1-5 μg/ml

    Final working dilutions must be determined by end user.
    生物信息
    免疫原品种 Human plasma fibronectin.
    表位 C-terminus
    克隆 868A11
    宿主 Mouse
    特异性 The C-terminal domain which contains the second fibrin binding site and it distinguishes between two major proteolytic fragments (140kd and 160dk), but not between the A and B chains. Epitope = C-terminal heparin binding fragment.
    同种型 IgG1
    品种反应性 Human
    抗体类型 Monoclonal Antibody
    Entrez基因编号
    • NM_212482.1
    • NM_002026.2
    • NM_054034.2
    • NM_212474.1
    • NM_212475.1
    • NM_212476.1
    • NM_212478.1
    Entrez基因汇总 This gene encodes fibronectin, a glycoprotein present in a soluble dimeric form in plasma, and in a dimeric or multimeric form at the cell surface and in extracellular matrix. Fibronectin is involved in cell adhesion and migration processes including embryogenesis, wound healing, blood coagulation, host defense, and metastasis. The gene has three regions subject to alternative splicing, with the potential to produce 20 different transcript variants. However, the full-length nature of some variants has not been determined.
    基因符号
    • FINC
    • FN1
    • DKFZp686H0342
    • DKFZp686I1370
    • MSF
    • CIG
    • LETS
    • DKFZp686O13149
    • FN
    • DKFZp686F10164
    UniProt编号
    • P02751
    UniProt汇总 FUNCTION: SwissProt: P02751 # Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Interaction with TNR mediates inhibition of cell adhesion and neurite outgrowth (By similarity).
    SIZE: 2386 amino acids; 262607 Da
    SUBUNIT: Mostly heterodimers or multimers of alternatively spliced variants, connected by 2 disulfide bonds near the carboxyl ends; to a lesser extent homodimers. Interacts with FBLN1, AMBP, TNR, LGALS3BP and COL13A1.
    SUBCELLULAR LOCATION: Secreted, extracellular space, extracellular matrix.
    TISSUE SPECIFICITY: Plasma FN (soluble dimeric form) is secreted by hepatocytes. Cellular FN (dimeric or cross-linked multimeric forms), made by fibroblasts, epithelial and other cell types, is deposited as fibrils in the extracellular matrix. Ugl-Y1, Ugl-Y2 and Ugl-Y3 are found in urine.DEVELOPMENTAL STAGE: Ugl-Y1, Ugl-Y2 and Ugl-Y3 are present in the urine from 0 to 17 years of age.
    PTM: Sulfated.
    SIMILARITY: SwissProt: P02751 ## Contains 12 fibronectin type-I domains. & Contains 2 fibronectin type-II domains. & Contains 16 fibronectin type-III domains.
    产品使用声明
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Maintain refrigerated at 2-8°C.
    包装信息
    数量 500 µg

    merck millipore,默克密理博,MAB1935,Anti-Fibronectin Antibody, CT, clone 868A11

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