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merck millipore,默克密理博,220005,CGP-37157 - CAS 75450-34-9 - Calbiochem
产品名称：CGP-37157 - CAS 75450-34-9 - Calbiochem
产品型号：220005
A cell-permeable benzothiazepine derivative of clonazepam that acts as a specific and potent inhibitor of the mitochondrial Na+/Ca2+ exchanger (IC₅₀ = 360 nM).
merck millipore,默克密理博,220005,CGP-37157 - CAS 75450-34-9 - Calbiochem
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重要规格表
经验配方 CAS号 C₁₅H₁₁Cl₂NOS 75450-34-9 描述 概述 A cell-permeable benzothiazepine derivative of clonazepam that acts as a specific and potent inhibitor of the mitochondrial Na+/Ca2+ exchanger (IC50 = 360 nM). Enhances the export of Ca2+ from isolated mitochondria. Also reported to directly inhibit voltage-gated Ca2+ channels. 产品目录编号 220005 品牌系列 Calbiochem®
同义词 7-Chloro-5-(2-chlorophenyl)-1,5-dihydro-4,1-benzothiazepin-2(3H)-one 参考 参考 Jornot, L., et al. 1999. J. Cell Sci. 112, 1013.
Babcock, D.F., et al. 1997. J. Cell Biol. 136, 833.
Baron. K.T., and Thayer, S.A. 1997. Eur. J. Pharmacol. 340, 295.
Griffiths, E.J., et al. 1997. Cell Calcium 21, 321.
White, R.J., and Reynolds, I.J. 1996, J. Neurosci. 16, 5688.
Cox, D.A., et al. 1993. J. Cardivasc. Pharmacol. 21, 595.
Cox, D.A., and Matlib, M.A. 1993. J. Biol. Chem. 268, 938.产品信息 CAS号 75450-34-9 具有ATP竞争性 N 形式 White solid Hill配方 C₁₅H₁₁Cl₂NOS 化学配方 C₁₅H₁₁Cl₂NOS Molar Mass 324.2 可逆 N 结构配方图像 生物信息 主靶 Mitochondrial Na+/Ca2+ exchanger 主靶IC50 360 nM against mitochondrial Na+/Ca2+ exchanger 纯度 ≥98% by HPLC 理化信息 细胞可渗透 Y 溶解度 DMSO 储存和货运信息 货运代码 Ambient Temperature Only
毒性 Standard Handling
储存 +2°C to +8°C
避光 Protect from light
无需冷冻 No
特殊指南 Following reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C. 包装信息 惰性气体下包装 Packaged under inert gas
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