merck millipore,默克密理愽
  • merck millipore,默克密理博,CBL450F,Anti-ICAM-1 Antibody, clone 15.2, FITC conjugated

  • merck millipore,默克密理博,CBL450F,Anti-ICAM-1 Antibody, clone 15.2, FITC conjugated

    产品名称：Anti-ICAM-1 Antibody, clone 15.2, FITC conjugated
    产品型号：CBL450F
    This Anti-ICAM-1 Antibody, clone 15.2, FITC conjugated is validated for use in FC, IH for the detection of ICAM-1d.

    merck millipore,默克密理博,CBL450F,Anti-ICAM-1 Antibody, clone 15.2, FITC conjugated

  • 产品介绍
  • merck millipore,默克密理博,CBL450F,Anti-ICAM-1 Antibody, clone 15.2, FITC conjugated

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    HIHC, FCMFITCMonoclonal Antibody
    描述
    产品目录编号 CBL450F
    品牌系列 Chemicon®
    商名
    • Chemicon
    描述 Anti-ICAM-1 Antibody, clone 15.2, FITC conjugated
    Alternate Names
    • CD54
    产品信息
    格式 FITC
    演示 The conjugate is supplied as a liquid in phosphate buffered saline containing 10mM sodium azide and 1 mg/mL bovine serum albumin
    应用
    应用 This Anti-ICAM-1 Antibody, clone 15.2, FITC conjugated is validated for use in FC, IH for the detection of ICAM-1d.
    主要应用
    • Immunohistochemistry
    • Flow Cytometry
    应用说明 ICAM-1 is a lymphokine inducable molecule and may be used in studies of LFA-1 mediated adhesion

    Optimal working dilutions must be determined by the end user.
    生物信息
    免疫原品种 Rheumatoid synovial cells and fibronectin adherent monocytes
    克隆 15.2
    宿主 Mouse
    特异性 This antibody recognizes ICAM-1, a 90 kDa integral membrane glycoprotein with seven potential N-linked glycosylation sites. ICAM-1 is the principal ligand of LFA-1. ICAM-1 is a lymphokine inducable molecule and may be used in studies of LFA-1 mediated adhesion. The antigen is expressed on endothelial cells and many other types of cells on activation including lymphocytes and fibroblasts.
    FUSION PARTNER: SP2/0 myeloma cell line
    同种型 IgG1
    品种反应性 Human
    抗体类型 Monoclonal Antibody
    Entrez基因编号
    • NM_000201.1
    Entrez基因汇总 ICAM1 (CD54) is typically expressed on endothelial cells and cells of the immune system. ICAM1 binds to integrins of type CD11a / CD18, or CD11b / CD18. ICAM1 is also exploited by Rhinovirus as a receptor.
    基因符号
    • ICAM-1
    • ICAM1
    • P3.58
    • BB2
    • CD54
    UniProt编号
    • P05362
    UniProt汇总 FUNCTION: SwissProt: P05362 # ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). In case of rhinovirus infection acts as a cellular receptor for the virus. Also acts as receptor for some coxsackieviruses.
    SIZE: 532 amino acids; 57825 Da
    SUBUNIT: Interacts with human herpesvirus 8 MIR2 protein (Probable).
    SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.
    PTM: Monoubiquitinated, which is promoted by MARCH9 and leads to endocytosis.
    SIMILARITY: SwissProt: P05362 ## Belongs to the immunoglobulin superfamily. ICAM family. & Contains 5 Ig-like C2-type (immunoglobulin-like) domains.
    产品使用声明
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Store at 2-8°C protected from light for uyp to 12 months from date of receipt. DO NOT FREEZE.
    包装信息
    数量 100 assays

    merck millipore,默克密理博,CBL450F,Anti-ICAM-1 Antibody, clone 15.2, FITC conjugated

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