merck millipore,默克密理愽
  • merck millipore,默克密理博,551476,InSolution™ Q-VD-OPh, Non-O-methylated - Calbiochem

  • merck millipore,默克密理博,551476,InSolution™ Q-VD-OPh, Non-O-methylated - Calbiochem

    产品名称：InSolution™ Q-VD-OPh, Non-O-methylated - Calbiochem
    产品型号：551476
    A cell-permeable, irreversible, broad-spectrum caspase inhibitor with effective antiapoptotic properties against all major caspase-mediated cellular apoptosis pathways.

    merck millipore,默克密理博,551476,InSolution™ Q-VD-OPh, Non-O-methylated - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,551476,InSolution™ Q-VD-OPh, Non-O-methylated - Calbiochem

    重要规格表

    经验配方
    C₂₆H₂₅F₂N₃O₆
    描述
    概述 A cell-permeable, irreversible, broad-spectrum caspase inhibitor (IC50 = 50, 100, 430, and <25 nM for caspase-1,-8, -9, and -3, respectively) with effective antiapoptotic properties against all major caspase-mediated cellular apoptosis pathways. Exhibits no cytotoxic effects even at extremely high concentrations. Shown to reduce ischemic brain damage and stroke-induced programmed cell death in thymus and spleen.
    产品目录编号 551476
    品牌系列 Calbiochem®
    同义词 N-(2-Quinolyl)valyl-aspartyl-(2,6-difluorophenoxy)methyl Ketone
    参考
    参考 Braun, J.S., et al. 2007. Exp. Neurol. 206, 183.
    Caserta, T.M., et al. 2003. Apoptosis 8, 345.
    Rebbaa, A., et al. 2003. Oncogene 22, 2805.
    产品信息
    具有ATP竞争性 N
    形式 Liquid
    配方 Supplied as a 10 mM (1 mg/195 µl) solution in DMSO.
    Hill配方 C₂₆H₂₅F₂N₃O₆
    化学配方 C₂₆H₂₅F₂N₃O₆
    Molar Mass 513.8
    吸湿 Hygroscopic
    肽序列 Q-Val-Asp-CH₂-OPh
    可逆 N
    结构配方图像
    生物信息
    主靶 caspase-1
    主靶IC50 50, 100, 430, and <25 nM for caspase-1,-8, -9, and -3, respectively
    纯度 ≥90% by HPLC
    理化信息
    细胞可渗透 Y
    肽序列 Q-Val-Asp-CH₂-OPh
    储存和货运信息
    货运代码 Shipped with Blue Ice or with Dry Ice
    毒性 Irritant
    储存 -20°C
    避光 Protect from light
    吸湿 Hygroscopic
    无需冷冻 No
    特殊指南 Following initial thaw, aliquot and freeze (-20°C).
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,551476,InSolution™ Q-VD-OPh, Non-O-methylated - Calbiochem

上一件merck millipore产品：merck millipore,默克密理博,14-479,Rsk1/MAPKAP Kinase 1a Protein, active, Rat, 10 µg
下一件merck millipore产品：merck millipore,默克密理博,676503,VEGFR/Tie-2/PDGFR Tyrosine Kinase Inhibitor - Calbiochem


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