merck millipore,默克密理愽
  • merck millipore,默克密理博,07-181,Anti-AMPK α-pan Antibody

  • merck millipore,默克密理博,07-181,Anti-AMPK α-pan Antibody

    产品名称：Anti-AMPK α-pan Antibody
    产品型号：07-181
    Anti-AMPK α-pan Antibody is an antibody against AMPK α-pan for use in WB.

    merck millipore,默克密理博,07-181,Anti-AMPK α-pan Antibody

  • 产品介绍
  • merck millipore,默克密理博,07-181,Anti-AMPK α-pan Antibody

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    R, HWBRbAffinity PurifiedPolyclonal Antibody
    描述
    产品目录编号 07-181
    品牌系列 Upstate
    商名
    • Upstate
    描述 Anti-AMPK α-pan Antibody
    产品信息
    格式 Affinity Purified
    控制
    • Rat liver preparation
    演示 Protein A Purified immunoglobulin in 30% glycerol, 0.07M Tris-glycine, pH 7.4, 0.105 M NaCl, 0.035% sodium azide as a preservative.
    应用
    应用 Anti-AMPK α-pan Antibody is an antibody against AMPK α-pan for use in WB.
    主要应用
    • Western Blotting
    生物信息
    免疫原品种 human AMP-activated protein a1 catalytic subunit (AEKQKHDGRVKIGHYILGD)
    宿主 Rabbit
    特异性 Recognizes AMP-activated protein kinase alpha subunits.
    同种型 IgG
    品种反应性 RatHuman
    抗体类型 Polyclonal Antibody
    Entrez基因编号
    • NM_006251, NM_006252
    Entrez基因汇总 The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
    基因符号
    • AMPKa1
    • PRKAA1
    • MGC57364
    • AMPK
    • AMPK1
    • MGC33776
    纯化方法 Immunoaffinity purified
    UniProt编号
    • P54646
    • Q13131
    UniProt汇总 FUNCTION: SwissProt: Q13131 # Responsible for the regulation of fatty acid synthesis by phosphorylation of acetyl-CoA carboxylase. It also regulates cholesterol synthesis via phosphorylation and inactivation of hormone-sensitive lipase and hydroxymethylglutaryl-CoA reductase. Appears to act as a metabolic stress-sensing protein kinase switching off biosynthetic pathways when cellular ATP levels are depleted and when 5'-AMP rises in response to fuel limitation and/or hypoxia. This is a catalytic subunit.
    COFACTOR: Magnesium.
    SIZE: 550 amino acids; 62808 Da
    SUBUNIT: Heterotrimer of an alpha catalytic subunit, a beta and a gamma non-catalytic subunits. Interacts with FNIP1.
    SIMILARITY: SwissProt: Q13131 ## Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily. & Contains 1 protein kinase domain.
    产品使用声明
    质量保证 routinely evaluated by immunoblot on a rat liver protein preparation
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Maintain for 2 years at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
    包装信息
    数量 200 µg

    merck millipore,默克密理博,07-181,Anti-AMPK α-pan Antibody

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