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重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 M IHC, WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 ABT331 描述 Anti-Nephrin Antibody Alternate Names - Renal glomerulus-specific cell adhesion receptor
- Nephrin
- NPHN
- NPHS1
背景信息 Nephrin (NPHS1, NPHN), also known as is Renal glomerulus-specific cell adhesion receptor, is strongly expressed in renal glomeruli and is a member of the immunoglobulin family of cell adhesion molecules. Mutations in the Nephrin gene result in congenital nephrotic syndrome, an autosomal-recessive disorder characterized by massive proteinuria in utero and nephrosis at birth. Renal glomeruli allow normal kidneys to filter plasma so that it is very pure. Nephrin is expressed in the podocyte slit-diaphragm of the renal glomeruli in a manner that suggests that Nephrin molecules homodimerize in an anti-parallel fashion similar to cadherin interactions in adherens junctions. Thus, Nephrin may constitute the entire extracellular structure of the slit-diaphragm. 产品信息 格式 Affinity Purified 控制 - Mouse kidney tissue lysate
演示 Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide. 应用 应用 Detect Nephrin using this rabbit polyclonal antibody, Anti-Nephrin Antibody validated for use in western blotting, IHC & Immunofluorescence. 主要应用 - Immunohistochemistry
- Western Blotting
应用说明 Immunohistochemistry Analysis: 1 µg/mL from a representative lot detected Nephrin in mouse kidney tissue.
Immunofluorescence Analysis: 10 µg/mL from a representative lot detected Nephrin in mouse kidney tissue.生物信息 免疫原品种 KLH-conjugated linear peptide corresponding to human Nephrin. 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 品种反应性 Mouse Species Reactivity Note Demonstrated to react with Mouse. Predicted to react with Human based on immunogen design. 抗体类型 Polyclonal Antibody 基因符号 - NPHS1
纯化方法 Antigen Affinity purified UniProt编号 - O60500
产品使用声明 质量保证 Evaluated by Western Blotting in mouse kidney tissue lysate.
Western Blotting Analysis: 1 µg/mL of this antibody detected Nephrin in 15 µg of mouse kidney tissue lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
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下一件merck millipore产品：merck millipore,默克密理博,MABS410,Anti-TPX2 Antibody, clone 18D5
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