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merck millipore,默克密理博,AB5384,Anti-Nitric Oxide Synthase II Antibody
产品名称：Anti-Nitric Oxide Synthase II Antibody
产品型号：AB5384
Detect Nitric Oxide Synthase II using this Anti-Nitric Oxide Synthase II Antibody validated for use in WB, IH.
merck millipore,默克密理博,AB5384,Anti-Nitric Oxide Synthase II Antibody
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 H IHC, WB Rb Serum Polyclonal Antibody 描述 产品目录编号 AB5384 品牌系列 Chemicon®
商名 - Chemicon
描述 Anti-Nitric Oxide Synthase II Antibody Alternate Names - iNOS
- NOS II
背景信息 The inducible isoform of the enzyme nitric oxide synthase (iNOS, NOS-II) is synthesized by macrophages and many other cell types in response to proinflammatory cytokines and certain other stimuli, such as hypoxia and stress. 产品信息 格式 Serum 演示 Rabbit serum. Liquid containing 0.05% sodium azide. 应用 应用 Detect Nitric Oxide Synthase II using this Anti-Nitric Oxide Synthase II Antibody validated for use in WB, IH. 主要应用 - Immunohistochemistry
- Western Blotting
应用说明 Western blot: 1:1,000-1:2,500 (ECL).
Immunohistochemistry: 1:2,500-1:6,000 (ABC).
Optimal working dilutions must be determined by end user.生物信息 免疫原品种 C-terminal 19 amino acid peptide from human chondrocyte nitric oxide synthase. 宿主 Rabbit 特异性 Inducible nitric oxide synthase (iNOS, NOS-II). No cross-reaction with nNOS and eNOS by immunohistochemistry. AB5384 reacts with human glia and certain neurons in Alzheimer's disease by immunohistochemistry. 品种反应性 Human 抗体类型 Polyclonal Antibody Entrez基因编号 - NM_000625.3
- NM_153292.1
Entrez基因汇总 Nitric oxide is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. This gene encodes a nitric oxide synthase which is expressed in liver and is inducible by a combination of lipopolysaccharide and certain cytokines. Three related pseudogenes are located within the Smith-Magenis syndrome region on chromosome 17. 基因符号 - EC 1.14.13.39
- NOS2A
- iNOS
- HEP-NOS
- INOS
- NOS
- NOS2
UniProt编号 - P35228
UniProt汇总 FUNCTION: SwissProt: P35228 # Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In macrophages, NO mediates tumoricidal and bactericidal actions.
COFACTOR: Heme group (By similarity). & Binds 1 FAD (By similarity). & Binds 1 FMN (By similarity). & Metrahydrobiopterin (BH4). May stabilize the dimeric form of the enzyme (By similarity).
SIZE: 1153 amino acids; 131117 Da
SUBUNIT: Homodimer. Binds SLC9A3R1.
TISSUE SPECIFICITY: Expressed in the liver, retina, bone cells and airway epithelial cells of the lung. Not expressed in the platelets.
SIMILARITY: SwissProt: P35228 ## Belongs to the NOS family. & Contains 1 flavodoxin-like domain.产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Maintain frozen at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles. 包装信息 数量 50 µL
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