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merck millipore,默克密理博,MABS410,Anti-TPX2 Antibody, clone 18D5
产品名称：Anti-TPX2 Antibody, clone 18D5
产品型号：MABS410
Detect Tpx2 using this mouse monoclonal antibody, Anti-TPX2 Antibody, clone 18D5 validated for use in western blotting, Immunofluorescence & IHC.
merck millipore,默克密理博,MABS410,Anti-TPX2 Antibody, clone 18D5
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 H IHC, WB M Purified Monoclonal Antibody 描述 产品目录编号 MABS410 描述 Anti-TPX2 Antibody, clone 18D5 Alternate Names - TPX2
- Differentially expressed in cancerous and non-cancerous lung cells 2
- DIL-2
- Hepatocellular carcinoma-associated antigen 519
- Protein fls353
- Restricted expression proliferation-associated protein 100
- p100
- Targeting protein for Xklp2
背景信息 Targeting protein for Xklp2 (TPX2), also known as Differentially expressed in cancerous and non-cancerous lung cells 2 (DIL-2) or Restricted expression proliferation-associated protein 100 (p100), is a major spindle assembly factor belonging to the TPX2 family of proteins. Tpx2 is a required component in the normal assembly of mitotic spindles and, during apoptosis, for microtubules. It is also necessary to the nucleation of microtubules in a chromatin and/or kinetechore dependent manner. Tpx2 activates Aurora-A kinase through promotion of autophosphorylation, protects the activated kinase from dephosphorylation, and regulates its localization to spindle microtubules. Normal expression of Tpx2 is exclusive to proliferating cells, specifically those transitioning from G1/S to the termination of cytokinesis. Tissue expression has only been observed in lung cancer cell lines. TPX2 interacts with a large number of proteins including serine/threonine protein kinase 6, ribosomal protein 6, Bop-1, -tubulin, and nucleolin among others. 产品信息 格式 Purified 演示 Purified mouse monoclonal IgG1κ antibody in buffer containing PBS (pH 7.2) with up to 0.1% sodium azide. 应用 应用 Detect Tpx2 using this mouse monoclonal antibody, Anti-TPX2 Antibody, clone 18D5 validated for use in western blotting, Immunofluorescence & IHC. 主要应用 - Immunohistochemistry
- Western Blotting
应用说明 Immunofluorescence Analysis: 1-4 μg/mL from a representative lot detected TPX2 in HeLa cells.
Immunohistochemistry Analysis: A representative lot detected TPX2 in Immunohistochemistry.生物信息 免疫原品种 Amino Acid: 1-220 of human TPX2 克隆 18D5 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Mouse 同种型 IgG1κ 品种反应性 Human 抗体类型 Monoclonal Antibody 基因符号 - TPX2
纯化方法 Protein G purified UniProt编号 - Q9ULW0
产品使用声明 质量保证 Evaluated by Western Blotting in MOLT-4 nuclear extract.
Western Blotting Analysis: 1 μg/mL of this antibody detected TPX2 in MOLT-4 nuclear extract.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 The antibody solution should be stored undiluted at 2-8°C and protected from prolonged exposure to light. Do not freeze.
包装信息 数量 100 µg
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下一件merck millipore产品：merck millipore,默克密理博,423500,Anti-Klotho Rabbit pAb
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