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品种反应性 主要应用 宿主 格式 抗体类型 H WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 ABS615 描述 Anti-PHIP Antibody Alternate Names - WD repeat-containing protein 11
- PH-interacting protein
- PHIP
- IRS-1 PH domain-binding protein
背景信息 The protein named PH-interacting protein (PHIP), or pleckstrin homology domain of insulin receptor substrate -1 or alternatively IRS-1 PH domain-binding protein or WD repeat-containing protein 11 and encoded by the human gene named PHIP/WDR11 is a transcriptional regulator highly important in insulin and insulin-like growth factor (IGF) signaling pathways. PHIP plays roles in cell proliferation, anti-apoptotic response, cell morphology, pancreatic beta cell growth and survival and cytoskeletal reorganization. PHIP binds IRS1 and IRS2 response elements and can directly interact with histones H1, H3, and H4. PHIP is expressed in a variety of cells and particularly high in various cancer and myeloma cells, and PHIP is a potential biomarker and mediator of metastasis in many cancers. We offer a rabbit polyclonal Anti-PHIP Antibody that has been validated in western blot on A375 cell extracts. 产品信息 格式 Affinity Purified 演示 Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide and 50% glycerol. 应用 应用 Anti-PHIP Antibody is a highly specific rabbit polyclonal antibody, that targets PH-interacting protein (PHIP) & has been tested in western blotting. 主要应用 - Western Blotting
生物信息 免疫原品种 Histidine-tagged fusion protein corresponding to human PHIP. 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 品种反应性 Human 抗体类型 Polyclonal Antibody 基因符号 - WDR11
- PHIP
纯化方法 Antigen Affinity purified UniProt编号 - Q8WWQ0
产品使用声明 质量保证 Evaluated by Western Blotting in A375 cell lysate.
Western Blotting Analysis: A 1:3,000 dilution of this antibody detected PHIP in A375 cell lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.包装信息 数量 150 µL
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