• merck millipore,默克密理博,516481,Pepstatin A, Synthetic - CAS 26305-03-3 - Calbiochem
  • merck millipore,默克密理博,516481,Pepstatin A, Synthetic - CAS 26305-03-3 - Calbiochem

    产品名称:Pepstatin A, Synthetic - CAS 26305-03-3 - Calbiochem
    产品型号:516481
    A reversible inhibitor of aspartic proteases.

    merck millipore,默克密理博,516481,Pepstatin A, Synthetic - CAS 26305-03-3 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,516481,Pepstatin A, Synthetic - CAS 26305-03-3 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₃₄H₆₃N₅O₉26305-03-3
    描述
    概述 A reversible inhibitor of aspartic proteases. Inhibits cathepsin D, pepsin, and renin. Reported to block apoptosis induced by CA-074 (Cat. No. 205530) in PC12 cell lines. Also available as a 25 mM solution in DMSO (Cat. No. 508437).
    Effective concentration: 1.0 µM.
    产品目录编号 516481
    品牌系列 Calbiochem®
    同义词 Iva-Val-Val-Sta-Ala-Sta, Isovaleryl-Val-Val-4-amino-3-hydroxy-6-methylheptanoyl-Ala-4-amino-3-hydroxy-6-methylheptanoic Acid
    参考
    参考 Isahara, K., et al. 1999. Neuroscience 91, 233.
    Kanamori, S., et al. 1998. Biochem. Biophys. Res. Commun. 251, 204.
    Szewczuk, Z., et al. 1992. Int. J. Pept. Prot. Res. 40, 233.
    Carraway, R.E., et al. 1991. Peptides 12, 107.
    Eid, M., et al. 1981. Biochem. J. 197, 465.
    Umezawa, H., et al. 1970. J. Antibiot. 23, 259.
    产品信息
    CAS号 26305-03-3
    具有ATP竞争性 N
    形式 White solid
    Hill配方 C₃₄H₆₃N₅O₉
    化学配方 C₃₄H₆₃N₅O₉
    Molar Mass 685.9
    光学旋转 Optical rotation: -90.0 ± 5° (c = 0.5, MeOH, 20°C).
    可逆 Y
    生物信息
    主靶 cathepsin D
    主靶IC50 EC50 = 1.0 µM in blocking apoptosis induced by CA-074 in PC12 cell lines
    纯度 ≥98% by HPLC
    理化信息
    细胞可渗透 N
    溶解度 DMSO or MeOH
    GHS安全信息
    RTECS SC6155000
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 +2°C to +8°C
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 4 months at -20°C.

    merck millipore,默克密理博,516481,Pepstatin A, Synthetic - CAS 26305-03-3 - Calbiochem

上一件merck millipore产品:merck millipore,默克密理博,235400,Caspase-3 Substrate I, Colorimetric - CAS 1177131-27-9 - Calbiochem
下一件merck millipore产品:merck millipore,默克密理博,ABC335,Anti-MTCH2 Antibody



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