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merck millipore,默克密理博,235400,Caspase-3 Substrate I, Colorimetric - CAS 1177131-27-9 - Calbiochem
产品名称:Caspase-3 Substrate I, Colorimetric - CAS 1177131-27-9 - Calbiochem
产品型号:235400
Colorimetric substrate for caspase-3 (Km = 9.7 µM) and related cysteine proteases.
merck millipore,默克密理博,235400,Caspase-3 Substrate I, Colorimetric - CAS 1177131-27-9 - Calbiochem
- 产品介绍
重要规格表
描述 概述 Colorimetric substrate for caspase-3 (Km = 9.7 µM) and related cysteine proteases. Sequence is based on the P1-P4 tetrapeptide cleavage site of poly(ADP-ribose) polymerase (PARP) and includes Asp216. Caspase-3 is the protease responsible for the cleavage of PARP. Also a substrate for caspase-6, caspase-7, caspase-8, and caspase-10. Cleavage of pNA is monitored colorimetrically at ~405 nm. 产品目录编号 235400 品牌系列 Calbiochem®
同义词 Ac-DEVD-pNA 参考 参考 Cardone, M.H., et al. 1998. Science 282, 1318.
Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.
Nicholson, D.W., et al. 1995. Nature 376, 37.
Lazebnik, Y.A., et al. 1994. Nature 371, 346.产品信息 CAS号 1177131-27-9 具有ATP竞争性 N 形式 Lyophilized Hill配方 C₂₆H₃₄N₆O₁₃ 化学配方 C₂₆H₃₄N₆O₁₃ Molar Mass 638.6 肽序列 Ac-Asp-Glu-Val-Asp-pNA 可逆 N 结构配方图像 生物信息 主靶 Caspas-3 主靶IC50 Km = 9.7 µM as colorimetric substrate for caspase-3 纯度 ≥95% by HPLC 理化信息 细胞可渗透 N 溶解度 DMSO 肽序列 Ac-Asp-Glu-Val-Asp-pNA 储存和货运信息 货运代码 Ambient Temperature Only
毒性 Standard Handling
储存 -20°C
避光 Protect from light
防潮 Protect from moisture
无需冷冻 No
特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
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