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merck millipore,默克密理博,04-964,Anti-Interleukin 4 (IL-4) Antibody, clone 11.B.11
产品名称：Anti-Interleukin 4 (IL-4) Antibody, clone 11.B.11
产品型号：04-964
This Anti-Interleukin 4 (IL-4) Antibody, clone 11.B.11 is validated for use in FC, EA for the detection of Interleukin 4 (IL-4).
merck millipore,默克密理博,04-964,Anti-Interleukin 4 (IL-4) Antibody, clone 11.B.11
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 M FC R Purified Monoclonal Antibody 描述 产品目录编号 04-964 描述 Anti-Interleukin 4 (IL-4) Antibody, clone 11.B.11 Alternate Names - interleukin 4
- B cell growth factor 1
- B-cell stimulatory factor 1
- B_cell stimulatory factor 1
- Lymphocyte stimulatory factor 1
背景信息 Interleukin-4 (IL-4) is a cytokine that stimulates activated B-cell and T-cell proliferation and induces differentiation of naive helper T cells (Th0 cells) to Th2 cells. These Th2 cells, in turn, also produce IL-4. IL-4 also acts as a key regulator in humoral and adaptive immunity and induces B-cell class switching to IgE, as well as up-regulating MHC class II production. Mutations in the IL-4 gene may lead to a susceptibility to ischemic stroke or cerebral infarction. Overproduction of IL-4 is associated with allergies. 产品信息 格式 Purified 控制 - MiCK-2™ cells
演示 Purified rat monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.05% sodium azide. 应用 应用 This Anti-Interleukin 4 (IL-4) Antibody, clone 11.B.11 is validated for use in FC, EA for the detection of Interleukin 4 (IL-4). 主要应用 - Flow Cytometry
应用说明 Functional Activity Assay: A previous lot was utilized by an independent laboratory to show increased resistance of mice to Listeria monocytogenes infection after administration of anti-interleukin 4 (IL-4), clone 11.B.11. (Haak-Frendscho, M., et al., 1992). 生物信息 免疫原品种 Recombinant protein corresponding to mouse IL-4. 表位 Unknown 克隆 11B11 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rat 特异性 This antibody recognizes IL-4. 同种型 IgG1κ 品种反应性 Mouse Species Reactivity Note Demonstrated to react with mouse. 抗体类型 Monoclonal Antibody Entrez基因编号 - NP_067258.1
基因符号 - IL-4
- IL4
- Binetrakin
- Pitrakinra
- BSF1
- BSF-1
纯化方法 Protein G purfied UniProt编号 - P07750
UniProt汇总 FUNCTION: Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes.
SUBCELLULAR LOCATION: Secreted.
SEQUENCE SIMILARITIES: Belongs to the IL-4/IL-13 family.产品使用声明 质量保证 Evaluated by Flow Cytometry in MiCK-2™ cells.
Flow Cytometry Analysis: 10 µg of this antibody detected IL-4 in MiCK-2™ cells.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
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