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品种反应性 主要应用 宿主 格式 抗体类型 H WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 ABS518 描述 Anti-SLC5A3 Antibody Alternate Names - Solute carrier family 5 member 3
- Sodium/myo-inositol cotransporter
- Na(+)/myo-inositol cotransporter
- Sodium/myo-inositol transporter 1
- SMIT1
背景信息 SLC5A3, also known as Sodium/myo-inositol cotransporter, Na (+)/myo-inositol cotransporter, Sodium/myo-inositol transporter 1 (SMT1), or Solute carrier family 5 member 3, and encoded by the gene SLC5A3, is an important intracellular transporter and signaling mediator that mediates the intracellular accumulation of myo-inositol. The compound myo-inositol is important for cell signaling both in the cytoplasm and in intracellular organelles. It is required in the plasma membrane and in the cytoplasm for maintaining the synthesis of the second messengers such as Inositol trisphosphate (IP3) and diacylglycerol (DAG) from phosphatidylinositol bisphosphate (PIP2). In organelles myo-inositol is a precursor for the synthesis of complex signaling phospholipids and inositolphosphates from IP3 and PIP2 as well. Moreover, SLC5A3 is upregulated by osmotic shock and downregulated by energy depletion and serves as a molecular sensor of cellular stress. 产品信息 格式 Affinity Purified 演示 Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. 应用 应用 Detect SLC5A3 using this Anti-SLC5A3 Antibody validated for use in western blotting & IHC (Paraffin). 主要应用 - Western Blotting
应用说明 Immunohistochemistry Analysis: A 1:500 dilution from a representative lot detected SLC5A3 in human prostate tissues.
Immunohistochemistry Analysis: A 1:2,000 dilution from a representative lot detected SLC5A3 in human placenta tissues.生物信息 免疫原品种 KLH-conjugated linear peptide corresponding to the cytoplasmic domain of human SLC5A3. 表位 cytoplasmic domain 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 品种反应性 Human 抗体类型 Polyclonal Antibody Entrez基因编号 - NP_008864
基因符号 - SLC5A3
纯化方法 Affinity purified UniProt编号 - P53794
产品使用声明 质量保证 Evaluated by Western Blotting in HUVEC cell lysate.
Western Blotting Analysis: 1 μg/mL of this antibody detected SLC5A3 in 10 μg of HUVEC cell lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
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