merck millipore,默克密理博,SF-1141,APP; Mouse, Cyanine 5 RNA Detection Probe,SmartFlare

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Merck Millipore 默克密理愽

Entrez Gene Number	Species Reactivity	Species Reactivity Note
NM_001198823.1	M	NM_007471.3, NM_001198824.1, NM_001198825.1, NM_001198826.1

描述
产品目录编号	SF-1141
商名	SmartFlare
描述	APP; Mouse, Cyanine 5 RNA Detection Probe \| SmartFlare
Alternate Names	Adap Ag Abpp
背景信息	With SmartFlare™ RNA Detection probes, you can detect RNA in LIVE CELLS with ease. With just an overnight incubation of APP; Mouse, Cyanine 5 RNA Detection Probe you can detect the presence of APP within your cells. Amyloid precursor protein (APP) is a type I integral membrane protein with a large N-terminal extracellular domain, a single transmembrane domain, and a short cytoplasmic tail. APP is cleaved by alpha-secretase to generate sAPPα and CTFα, which is the C-terminal membrane, associated product of α-secretase cleavage. α-secretase cleaves in the Aβ domain. β-secretase cleavage of APP at the N-terminal end of the Aβ sequence results in sAPPβ and CTFβ. Both CTFα and CTFβ are cleaved at the C-terminal end of the Aβ transmembrane domain to generate CTFɣ. The antibody (171610) detects CTFɣ fragment, which migrates at about 6 kDa on SDS-PAGE gels.

产品信息
格式	Cyanine 5
演示	Lyophilized

应用
应用	Use SmartFlare RNA Detection probes to measure gene expression in live cells. With an overnight incubation of SmartFlare APP, Human, Cyanine 5, you can detect APP RNA levels within your cells.
主要应用	RNA Detection

产品使用声明
质量保证	SmartFlare Probes have been tested in a buffer system to detect the release of the fluorophore in the presence of a complimentary base pair sequence for each lot to confirm target specificity. SmartFlare Probes have also been tested in a cell model system and demonstrated increased fluorescence in cells expressing the target compared to a negative SmartFlare Scramble Control.
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Store at 2–8°C in lyophilized format ONLY. Room temperature is required for reconstituted product.

包装信息
数量	250 reactions

merck millipore,默克密理博,SF-1141,APP; Mouse, Cyanine 5 RNA Detection Probe,SmartFlare

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