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品种反应性 主要应用 宿主 格式 抗体类型 H WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 ABS227 Replaces MABC654 描述 Anti-FKBP5 Antibody Alternate Names - Rotamase
- Peptidyl-prolyl cis-trans isomerase FKBP5
- 51 kDa FK506-binding protein
- 51 kDa FKBP
- FKBP-51
- 54 kDa progesterone receptor-associated immunophilin
- Androgen-regulated protein 6
- FF1 antigen
- FK506-binding protein 5
- FKBP-5
- FKBP54
- p54
- HSP90-binding immunophilin
背景信息 FK506 binding protein 51 (FKBP5) is a ubiquitous immunophilin, which has been implicated in multiple mood disorders such as depression, anxiety, and post-traumatic stress disorder, through its regulation of multiple enzymes, transcription factors, and other signaling molecules. It is also a well known co-chaperone of the Hsp90 protein, which regulates the signaling of the glucocorticoid receptor (GR), by a negative feedback mechanism. The expression of FKBP5 increases with rising glucocorticoid levels, and FKBP5 in turn decreases GR signaling by promoting nuclear translocation of GR isoforms. In contrast, FKBP5 functions as a positive regulator of the androgen receptor. 产品信息 格式 Affinity Purified 控制 - HEK293 cell lysate
演示 Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. 应用 应用 Anti-FKBP5 Antibody is an antibody against FKBP5 for use in Western Blotting. 主要应用 - Western Blotting
应用说明 Western Blot Analysis: 0.05 µg/mL of this antibody detected FKBP5 in 10 mg of K562 cell lysate. 生物信息 免疫原品种 KLH-conjugated linear peptide corresponding to human FKBP5. 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 品种反应性 Human Species Reactivity Note Demonstrated to react with Human and Mouse. Predicted to react with Bovine based on 100% sequence homology. Other homologies: Rat (92% sequence homology). 抗体类型 Polyclonal Antibody Entrez基因编号 - NP_004108
基因符号 - FKBP51
- FKBP5
- AIG6
纯化方法 Affinity purified UniProt编号 - Q13451
产品使用声明 质量保证 Evaluated by Western Blot in HEK293 cell lysate.
Western Blot Analysis: 0.05 mg/mL of this antibody detected FKBP5 in 10 mg of HEK293 cell lysate.储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 50 µg
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下一件merck millipore产品：merck millipore,默克密理博,07-1817,Anti-phospho-SRPK2 (Ser494) Antibody
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