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品种反应性 主要应用 宿主 格式 抗体类型 R, H, M ICC, WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 ABS208 描述 Anti-p115 RhoGEF Antibody Alternate Names - Sub1.5
- Rho guanine nucleotide exchange factor 1
- 115 kDa guanine nucleotide exchange factor
- p115-RhoGEF
- p115RhoGEF
背景信息 p115 RhoGEF (115 kDa guanine nucleotide exchange factor) is also called Rho guanine nucleotide exchange factor 1 or ARHGEF1. p115 RhoGEF is thought to play a role in the regulation of RhoA GTPase by guanine nucleotide-binding alpha-12 (GNA12) and alpha-13 (GNA13) subunits, and may mediates angiotensin-2-induced RhoA activation. p115 RhoGEF is ubiquitously expressed, and is most often found in the cytoplasm, however, it also translocates to the membrane upon activated GNA13 or LPA stimulation. 产品信息 格式 Affinity Purified 控制 - HEK293 cell lysate
演示 Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. 应用 应用 Anti-p115 RhoGEF Antibody is a highly specific rabbit polyclonal antibody, that targets p115 RhoGEF & has been tested in western blotting & ICC. 主要应用 - Immunocytochemistry
- Western Blotting
应用说明 Immunocytochemistry Analysis: A 1:100 dilution from a representative lot detected p115 RhoGEF in HeLa cells. 生物信息 免疫原品种 KLH-conjugated linear peptide corresponding to human p115 RhoGEF. 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 品种反应性 RatHumanMouse Species Reactivity Note Demonstrated to react with Human. Predicted to react with Mouse and Rat based on 100% sequence homology. 抗体类型 Polyclonal Antibody Entrez基因编号 - NP_004697
基因符号 - ARHGEF1
纯化方法 Affinity purified UniProt编号 - Q92888
产品使用声明 质量保证 Evaluated by Western Blotting in HEK293 cell lysate.
Western Blotting Analysis: 1.0 µg/mL of this antibody detected p115 RhoGEF in 10 µg of HEK293 cell lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
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