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品种反应性 主要应用 宿主 格式 抗体类型 H IHC, WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 ABF243 描述 Anti-CXCR7 Antibody Alternate Names - CXCR7
- C-X-C chemokine receptor type 7
- CXC-R7
- CXCR-7
- Chemokine orphan receptor 1
- G-protein coupled receptor 159
- G-protein coupled receptor RDC1 homolog
- RDC-1
背景信息 As a member of the G-protein coupled receptor 1 family, C-X-C chemokine receptor type 7 (CXCR7) serves as a receptor for chemokines CXCL12/SDF1 and CXL11 (I-TAC). Depending on the context, CXCR7 is observed to play multiple roles in cancer progression and survival, tumor invasion, cellular adhesion, ischemic stroke, and bone marrow HSC differentiation. CXCR7 activation results in beta-arrestin recruitment and subsequent MAPK signaling. Additionally, CXCR7 can exist as either a homodimer or heterodimerizes with CXCR4 to regulate CXCR4 signalling. 产品信息 格式 Affinity Purified 演示 Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide and 50% glycerol. 应用 应用 Anti-CXCR7 antibody is an antibody against CXCR7 for use in western blotting, IHC & immunofluorescence. 主要应用 - Immunohistochemistry
- Western Blotting
应用说明 Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected CXCR7 in human kidney tissue.
Immunofluorescence Analysis: A 1:25 dilution from a representative lot detected CXCR7 in HepG2 cells.生物信息 免疫原品种 KLH-conjugated linear peptide corresponding to human CXCR7. 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 品种反应性 Human 抗体类型 Polyclonal Antibody 基因符号 - RDC1
- CXCR7
- CMKOR1
- GPR159
纯化方法 Antigen Affinity purified UniProt编号 - P25106
产品使用声明 质量保证 Evaluated by Western Blotting in C6 cell lysate.
Western Blotting Analysis: A 1:400 dilution of this antibody detected CXCR7 in C6 cell lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.包装信息 数量 150 µL
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