merck millipore,默克密理博,ABN286,Anti-FOXM1 Antibody

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merck millipore,默克密理博,ABN286,Anti-FOXM1 Antibody
产品名称：Anti-FOXM1 Antibody
产品型号：ABN286
Detect the FOXM1 protein using this Anti-FOXM1 validated for use in WB & IHC.

merck millipore,默克密理博,ABN286,Anti-FOXM1 Antibody

产品介绍

merck millipore,默克密理博,ABN286,Anti-FOXM1 Antibody

重要规格表

品种反应性	主要应用	宿主	格式	抗体类型
R, H	IHC, WB	Rb	Affinity Purified	Polyclonal Antibody

描述
产品目录编号	ABN286
描述	Anti-FOXM1 Antibody
Alternate Names	Winged-helix factor from INS-1 cells Forkhead box protein M1 Forkhead-related protein FKHL16 Hepatocyte nuclear factor 3 forkhead homolog 11 HFH-11 HNF-3/fork-head homolog 11 M-phase phosphoprotein 2 MPM-2 reactive phosphoprotein 2 Transcription factor Trident
背景信息	Forkhead box M1 (FOXM1), also named HNF-3, HFH-11 or Trident, belongs to a superfamily of Fox transcription factors. FOXM1 is strongly associated with cell proliferation and plays an important role in cell cycle progression by regulating both G1/S and G2/M phases. FOXM1 is also involved in DNA damage repair, angiogenesis, apoptosis, and tissue regeneration. Recently, crucial roles of this transcription factor were found in the development and progression of many cancers including colorectal, lung, prostate, liver and breast cancer. FOXM1 levels are significantly higher and associated with tumor grade in most human tumors, rendering it a potential target of cancer diagnosis and therapies.

产品信息
格式	Affinity Purified
控制	Human testis tissue lysate
演示	Purified rabbit polyclonal in buffer containing PBS with 0.1% sodium azide and 50% glycerol.

应用
应用	Detect the FOXM1 protein using this Anti-FOXM1 validated for use in WB & IHC.
主要应用	Immunohistochemistry Western Blotting
应用说明	Western Blotting Analysis: A 1:1,000 dilution from a representative lot detected FOXM1 in 10 µg of A431 cell lysate. Immunohistochemistry Analysis: A 1:250 dilution from a representative lot detected FOXM1 in rat testis tissue.

生物信息
免疫原品种	GST-tagged recombinant protein corresponding to human FOXM1.
浓缩	Please refer to the Certificate of Analysis for the lot-specific concentration.
宿主	Rabbit
特异性	This antibody recognizes three isoforms: FOXM1-pp (~95-110 kDa), FOXM1-B (isoform 2, ~83 kDa), and FOXM1A (isoform 4, ~90 kDa).
品种反应性	RatHuman
Species Reactivity Note	Demonstrated to react with Human and Rat.
抗体类型	Polyclonal Antibody
基因符号	WIN FOXM1 FKHL16 HFH11 MPP2
纯化方法	Antigen Affinity purified
UniProt编号	Q08050

产品使用声明
质量保证	Evaluated by Western Blotting in human testis tissue lysate. Western Blotting Analysis: A 1:1,000 dilution of this antibody detected FOXM1 in 10 µg of human testis tissue lysate.
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.

储存和货运信息

存储条件

Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.