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品种反应性 主要应用 宿主 格式 抗体类型 R, H, M WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 ABN108 描述 Anti-pan-TUC Antibody Alternate Names - ULIP-2
- Dihydropyrimidinase-related protein 2
- DRP-2
- Collapsin response mediator protein 2
- CRMP-2
- N2A3
- Unc-33-like phosphoprotein 2
背景信息 TUC (TOAD [Turned On After Division]/Ulip/CRMP/DRP) is a family of proteins that have emerged as strong candidates for a role in neuronal growth cone signaling. The TUC family members reach their highest expression levels in early post-mitotic neurons during their peak periods of axonal growth. Data suggests that TUCs play a role in axonal outgrowth, pathfinding and possibly in the process that permits growing axons to choose proper routes and targets. TUCs are also necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Homotetramers, and heterotetramers with TUC proteins from the genes DPYSL1, DPYSL2, DPYSL3, DPYSL4 or DPYSL5. 产品信息 格式 Affinity Purified 控制 - Rat brain tissue lysate
演示 Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. 应用 应用 Detect the pan-TUC protein using this Anti-pan-TUC validated for use in WB & IHC. 主要应用 - Western Blotting
应用说明 Western Blot Analysis: A 1:25,000 dilution from a representative lot detected pan-TUC in panel of TUC proteins.
Immunhistochemistry Analysis: A 1:4,000 dilution from a representative lot detected pan-TUC in mouse embryonic eye, brain and GI tissues.生物信息 免疫原品种 KLH-conjugated linear peptide corresponding to a region near the N-terminus in the TUC family conserved region of human pan-TUC. 表位 Region near the N-terminus in the TUC family conserved domain. 宿主 Rabbit 特异性 This antibody recognizes a region near the N-terminus in the TUC family conserved domain of pan-TUC. 品种反应性 RatHumanMouse Species Reactivity Note Demonstrated to react with Human, Mouse, and Rat. (Note: Dihydropyrimidinase-related protein 4 (TUC4) is 87% identical to Human, Rat, and Mouse. Dihydropyrimidinase-related protein 3 (TUC3) is 100% identical in Human, Mouse, Rat, Xenopus, Bovine, and Chicken. Dihydropyrimidinase-related protein 2 (TUC2) is 100% identical in Human, Rat, Mouse, Bovine, and Chicken. Dihydropyrimidinase-related protein 1 (TUC1) is 87% identical in Mouse, Bovine, and Rat and 83% identical in human.) 抗体类型 Polyclonal Antibody Entrez基因编号 - NP_001377
基因符号 - ULIP2
- DPYSL2
- CRMP2
纯化方法 Affinity purified UniProt编号 - Q16555
产品使用声明 质量保证 Evaluated by Western Blotting in rat brain tissue lysate.
Western Blotting Analysis: A 1:10,000 dilution of this antibody detected pan-TUC in 10 µg of rat brain tissue lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µL
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