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品种反应性 主要应用 宿主 格式 抗体类型 A, R ELISA, IH(P) Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 ABN131 Replaces AB131 描述 Anti-GABA Antibody 背景信息 Neurotransmitters can be defined as chemical substances that are released by the presynaptic neuron before being bound by receptors on the postsynaptic cell surface. It has been well established that the nervous system utilizes neurotransmitters for cell signaling. Neurotransmitters can be divided into two groups; low molecular weight transmitter molecules such as biogenic amines, purines, or amino acids, and bioactive peptides, of which more than 50 members have been identified in the mammalian central nervous system. Many low molecular weight neurotransmitters are produced within the axon terminal from common cellular metabolites and packaged into synaptic vesicles. The transport and delivery of vesicles containing neurotransmitter is a highly regulated and complex process. GABA (g-aminobutyric acid) is the major inhibitory neurotransmitter in the central nervous system that is involved in the pathogenesis of certain neurological and psychiatric disorders. GABA is produced from glutamic acid in a reaction catalyzed by glutamic acid decarboxylase. GABA interacts with the GABAA and GABAB receptors, which are widely distributed throughout the nervous system and in a variety of cell types. The immunolocalization, neuronal distribution, and vesicular compartmentalization of neurotransmitter molecules and their precursors are important for understanding the modulation, regulation, and function of neurotransmitters in the nervous system. 产品信息 格式 Affinity Purified 控制 - Rat hypothalamus tissue
演示 Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. 应用 应用 Anti-GABA Antibody is a highly specific rabbit polyclonal antibody, that targets GABA & has been tested in IHC (Paraffin) & Enzyme Immunoassay (ELISA). 主要应用 - Enzyme Immunoassay (ELISA)
- Immunohistochemistry (Paraffin)
应用说明 Immunohistochemistry Analysis: A 1:500 dilution from a representative lot detected GABA in rat brain tissue (Note: Non-specific staining may be observed in vascular tissues.).
ELISA Analysis: A representative lot from an independent laboratory detected GABA in a competitive ELISA.生物信息 免疫原品种 BSA-conjugated GABA-Glutaraldehyde 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 特异性 This antibody is expected to demonstrate broad species reactivity. 品种反应性 AllRat Species Reactivity Note Demonstrated to react with Rat. 抗体类型 Polyclonal Antibody 纯化方法 Affinity purified 产品使用声明 质量保证 Evaluated by Immunohistochemisty in rat hypothalamus tissue.
Immunohistochemistry Analysis: A 1:500 dilution from a representative lot detected GABA in rat hypothalamus tissue (Note: Non-specific staining may be observed in vascular tissues.).使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
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