- 当前位置：首页 > >Merck Millipore > 生命科学研究
- 生命科学研究
- 产品介绍
描述 概述 Native, human C1q complement component. Glycoprotein composed of 18 polypeptide chains consisting of three nonidentical subunits, A, B, and C, of M.W. 29 kDa, 26 kDa, and 19 kDa, respectively. Present in normal human serum at 70 µg/ml. Found in circulating blood plasma complexed with two C1r and two C1s molecules to form the first component of complement (C1). Activation of complement via classical pathway is triggered by binding of C1q to immune complexes containing IgG or IgM or to a variety of other activating substances, including C-reactive protein, retroviruses, and mitochondria. Subsequent to C1q binding, C1r and C1s are converted to proteolytic enzymes that are responsible for continuation of activation via the classical pathway. 产品目录编号 204876 品牌系列 Calbiochem®
参考 参考 Loos, M., et al. 1980. J. Immunol. 124, 59.
Kolb, W.P., et al. 1979. J. Immunol. 122, 2103.产品信息 CAS号 80295-33-6 形式 Liquid 配方 In 300 mM NaCl, 10 mM HEPES, 40% glycerol, pH 7.2. Molar Mass 410000 生物信息 生物活性 ≥150,000 C1qH50 units/mg and ≥70% C1q activity in normal human serum on a mg/mg basis 纯度 ≥90% by SDS-PAGE 来源 Prepared from serum that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV. 浓缩标签 Please refer to vial label for lot-specific concentration
理化信息 污染物 IgG, IgA, IgM, C3, C4, albumin, fibrinogen, α₂-macroglobulin: ≤trace amounts 储存和货运信息 货运代码 Dry Ice Only
毒性 Standard Handling
储存 ≤ -70°C
避免冻结 / 解冻 Avoid freeze/thaw
无需冷冻 No
特殊指南 Following initial thaw, aliquot and freeze (-70°C).
上一件merck millipore产品：merck millipore,默克密理博,ACR5000PG,Protein G Reagent Kit
下一件merck millipore产品：merck millipore,默克密理博,MABC127,Anti-Ephrin-B2 Antibody
相关产品
merck millipore,默克密理博,ABN131,Anti-GABA Antibody
merck millipore,默克密理博,565763,γ-Secretase Inhibitor VI - CAS 287196-57-0 - Calbiochem
merck millipore,默克密理博,MCH100104,Muse Count &Viability Assay Kit (200X) - 100 Tests
merck millipore,默克密理博,ACR5000PG,Protein G Reagent Kit
merck millipore,默克密理博,MABC127,Anti-Ephrin-B2 Antibody
merck millipore,默克密理博,06-102,Anti-EGF Antibody, neutralizing
merck millipore,默克密理博,AB5622,Anti-Microtubule-Associated Protein 2 (MAP2) Antibody
merck millipore,默克密理博,AB15588,Anti-DCAMKL1 splice variant Antibody
merck millipore,默克密理博,AB119,Anti-Dopa Decarboxylase Antibody