merck millipore,默克密理博,ABF232,Anti-MICA Antibody

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merck millipore,默克密理博,ABF232,Anti-MICA Antibody
产品名称：Anti-MICA Antibody
产品型号：ABF232
Detect MHC class 1 polypeptide-related sequence A using this rabbit polyclonal antibody, Anti-MICA Antibody validated for use in western blotting.

merck millipore,默克密理博,ABF232,Anti-MICA Antibody

产品介绍

merck millipore,默克密理博,ABF232,Anti-MICA Antibody

重要规格表

品种反应性	主要应用	宿主	格式	抗体类型
H	WB	Rb	Affinity Purified	Polyclonal Antibody

描述
产品目录编号	ABF232
描述	Anti-MICA Antibody
Alternate Names	MICA MHC class I polypeptide-related sequence A MIC-A
背景信息	The protein MHC class 1 polypeptide-related sequence A (MIC-A) and encoded by the human gene named MICA is an unusual MHC class one molecule with no known role in antigen presentation but instead acts as a stress-induced self antigen that is recognized by gamma delta T cells and is the ligand for KLRK1/NKG2D cellular receptor. Binding to KLRK1 leads to cell lysis. MICA is a cell membrane associated protein found in the cytoplasm. Additionally, it is expressed in many organ systems and found expressed on many cell types. Expression is induced by many stress responses, including infection, DNA damaging agents, E. coli contact, hCMV and ionizing radiation. MICA is also the antigen for many autoimmune diseases associated with the skin, one organ system where MICA is highly expressed. Psoriasis and Psoriatic arthritis are two such diseases and antibodies to MICA have also been associated with organ transplant difficulties and allograft rejection. EMD-Millipore’s Anti-MICA rabbit polyclonal antibody has been tested in western blots on human brain tissue sections.

产品信息
格式	Affinity Purified
演示	Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide and 50% glycerol.

应用
应用	Detect MHC class 1 polypeptide-related sequence A using this rabbit polyclonal antibody, Anti-MICA Antibody validated for use in western blotting.
主要应用	Western Blotting

生物信息
免疫原品种	GST-tagged fusion protein corresponding to human MICA.
浓缩	Please refer to the Certificate of Analysis for the lot-specific concentration.
宿主	Rabbit
品种反应性	Human
Species Reactivity Note	Human
抗体类型	Polyclonal Antibody
基因符号	PERB11.1 MICA
纯化方法	Antigen Affinity purified
UniProt编号	Q29983

产品使用声明
质量保证	Evaluated by Western Blotting in human brain tissue lysate. Western Blotting Analysis: A 1:600 dilution of this antibody detected MICA in human brain tissue lysate.
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.

储存和货运信息

存储条件

Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.