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品种反应性 主要应用 宿主 格式 抗体类型 H IHC, WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 ABC267 描述 Anti-EXOSC10 Antibody Alternate Names - EXOSC10
- Exosome component 10
- Autoantigen PM/Scl 2
- P100 polymyositis-scleroderma overlap syndrome-associated autoantigen
- Polymyositis/scleroderma autoantigen 100 kDa
- PM/Scl-100
- Polymyositis/scleroderma autoantigen 2
背景信息 Exosome component 10 (EXOSC10) contains 1 3'-5' exonuclease domain and 1 HRDC domain. It is strongly enriched in the nucleolus and a small amount has been found in the cytoplasm supporting the existence of a nucleolar RNA exosome complex form. As a putative catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity, EXOSC10 participates in a multitude of cellular RNA processing and degradation events. 产品信息 格式 Affinity Purified 控制 - HeLa cell lysate
演示 Purified rabbit polyclonal in buffer containing PBS with 0.02% sodium azide and 50% glycerol. 应用 应用 Detect the EXOSC10 protein using this Anti-EXOSC10 validated for use in WB & IHC. 主要应用 - Immunohistochemistry
- Western Blotting
应用说明 Immunohistochemistry Analysis: A 1:50 dilution from a representative lot was detected EXOSC10 in human spleen tissue. 生物信息 免疫原品种 GST-tagged recombinant protein corresponding to human EXOSC10. 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 品种反应性 Human 抗体类型 Polyclonal Antibody 基因符号 - RRP6
- EXOSC10
- PMSCL
- PMSCL2
纯化方法 Antigen Affinity purified UniProt编号 - Q01780
产品使用声明 质量保证 Evaluated by Western Blotting in HeLa cell lysate.
Western Blotting Analysis: A 1:1,000 dilution of this antibody detected EXOSC10 in 30 µg of HeLa cell lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.包装信息 数量 150 µL
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