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重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 Eq, H, Po, Chp, Rhesus Macaque, Ca WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 ABE91 描述 Anti-JMJD8 Antibody Alternate Names - Jumonji domain-containing protein 8
- JMJD
- JmjC domain-containing protein 8
背景信息 Covalent modification of histones plays critical role in regulating chromatin structure and transcription. JMJD8 is one member of the family of JmjC domain-containing histone demethylation (JHDM) enzymes. These proteins remove specific methyl marks from histones. Histone demethylation by JHDM proteins requires cofactors Fe(II) and alpha-ketoglutarate. Contributions of histone demethylase activity to tumor development, decreases in cell proliferation, and hormone-dependent transcriptional activation have been observed. While two isoforms of JMJD8 have been described, further study is still required to clarify the roles and mechanisms of JMJD8 among other JHDM protein family members. 产品信息 格式 Affinity Purified 控制 - HeLa nuclear extract
演示 Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. 应用 应用 Anti-JMJD8 Antibody is a Rabbit Polyclonal Antibody for detection of JMJD8 also known as Jumonji domain-containing protein 8 & has been validated in WB. 主要应用 - Western Blotting
生物信息 免疫原品种 KLH-conjugated linear peptide corresponding to human JMJD8. 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 品种反应性 HorseHumanPigChimpanzeeRhesus MacaqueCanine Species Reactivity Note Demonstrated to react with Human. Predicted to react with Porcine, Chimpanzee, Rhesus Macaque, Canine, and Equine based on 100% sequence homology. 抗体类型 Polyclonal Antibody Entrez基因编号 - NP_001005920.2
基因符号 - PP14397
- JMJD8
- C16orf20
纯化方法 Affinity purified UniProt编号 - Q96S16
产品使用声明 质量保证 Evaluated by Western Blot in HeLa nuclear extract.
Western Blot Analysis: 1 mg/mL of this antibody dected JMJD8 in 10 mg of HeLa nuclear extract.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
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