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merck millipore,默克密理博,04-367,Anti-IRAK3 Antibody, rabbit monoclonal
产品名称：Anti-IRAK3 Antibody, rabbit monoclonal
产品型号：04-367
Please note that this product will not be available for sale after March 15, 2015. Please select one of the other antibodies against this target. Detect IRAK3 using this Anti-IRAK3 Antibody, rabbit More>>
merck millipore,默克密理博,04-367,Anti-IRAK3 Antibody, rabbit monoclonal
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 M, H WB Rb Purified Monoclonal Antibody 描述 产品目录编号 04-367 品牌系列 Upstate
商名 - Upstate
描述 Anti-IRAK3 Antibody, rabbit monoclonal Alternate Names - IRAKM
产品信息 格式 Purified 演示 100 µL of rabbit monoclonal IgG in 30 mM Tris-Glycine (pH 7.4), 0.09 M NaCl, 0.006% sodium azide and 0.03% BSA and 40% glycerol. 应用 应用 Please note that this product will not be available for sale after March 15, 2015. Please select one of the other antibodies against this target. Detect IRAK3 using this Anti-IRAK3 Antibody, rabbit validated for use in IP & WB. 主要应用 - Western Blotting
应用说明 Immunoblot Analysis: A 1:2,000 dilution of the lot detected IRAK3 CT in lysates from A431 cells.
Immunoprecipitation:
A 1:50 dilution of this antibody immunoprecipitated IRAK3 CT using protein G:agarose beads.
生物信息 免疫原品种 KLH-conjugated synthetic peptide corresponding to residues in the C-term of human IRAK-3 宿主 Rabbit 特异性 Recognizes the C-term domain of IRAK3. 同种型 IgG 品种反应性 MouseHuman 抗体类型 Monoclonal Antibody Entrez基因编号 - NM_007199.1
基因符号 - IRAK-M
- IRAK3
- IRAKM
- IRAK-3
- ASRT5
纯化方法 Serum UniProt编号 - Q9Y616
UniProt汇总 FUNCTION: SwissProt: Q9Y616 # Inhibits dissociation of IRAK1 and IRAK4 from the Toll- like receptor signaling complex by either inhibiting the phosphorylation of IRAK1 and IRAK4 or stabilizing the receptor complex (By similarity).
COFACTOR: Magnesium.
SIZE: 596 amino acids; 67753 Da
TISSUE SPECIFICITY: Expressed predominantly in peripheral blood lymphocytes.
DISEASE: SwissProt: Q9Y616 # Defects in IRAK3 are associated with susceptibility to asthma-related traits type 5 (ASRT5) [MIM:611064]. Asthma-related traits include clinical symptoms of asthma, such as coughing, wheezing, dyspnea, bronchial hyperresponsiveness as assessed by methacholine challenge test, serum IgE levels, atopy, and atopic dermatitis.
SIMILARITY: SwissProt: Q9Y616 ## Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. Pelle subfamily. & Contains 1 death domain. & Contains 1 protein kinase domain.产品使用声明 质量保证 Routinely evaluated by immunoblot. 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 2 years at -20°C from date of shipment 包装信息 数量 100 µL
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