• merck millipore,默克密理博,ABN455,Anti-C9ORF72/C9RANT (poly-GP) Antibody
  • merck millipore,默克密理博,ABN455,Anti-C9ORF72/C9RANT (poly-GP) Antibody

    产品名称:Anti-C9ORF72/C9RANT (poly-GP) Antibody
    产品型号:ABN455
    Anti-C9ORF72/C9RANT (poly-GP), Cat # ABN455, is a highly validated rabbit Polyclonal antibody, that targets C9ORF72/C9RANT (poly-GP) and has been tested in Western Blotting and Immunohistochemistry.

    merck millipore,默克密理博,ABN455,Anti-C9ORF72/C9RANT (poly-GP) Antibody

  • 产品介绍
  • merck millipore,默克密理博,ABN455,Anti-C9ORF72/C9RANT (poly-GP) Antibody

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    HWBRbUnpurifiedPolyclonal Antibody
    描述
    产品目录编号 ABN455
    描述 Anti-C9ORF72/C9RANT (poly-GP) Antibody
    Alternate Names
    • C9RANT
    • C9ORF72
    背景信息 In a noncoding region of C9ORF72 hexanucleotide (GGGGCC) repeat expansions are the major genetic cause of FTD and ALS (c9FTD/ALS). Transcripts that have the RNA structure of GGGGCC repeats are susceptible to an unconventional mechanism of translation called repeatassociated non-ATG (RAN) translation. Translation of the GGGGCC-repeat in all reading frames would result in three dipeptide-repeat (DPR) proteins poly-(Gly-Ala), poly-(Gly-Pro) and poly-(Gly-Arg). poly-GA and poly-GP proteins are extremely hydrophobic and may form intracellular aggregates. Anti-C9RANT, an antibody that was generated against putative GGGGCC repeat RANtranslated peptides mentioned above, detects insoluble high molecular weight material in brain homogenates, and neuronal inclusions throughout the CNS of c9FTD/ALS cases (Ash, PE, et al. (2013). Neuron. 77(4):639-46.)
    产品信息
    格式 Unpurified
    演示 Rabbit Polyclonal serum with 0.05% sodium azide.
    应用
    应用 Anti-C9ORF72/C9RANT (poly-GP), Cat # ABN455, is a highly validated rabbit Polyclonal antibody, that targets C9ORF72/C9RANT (poly-GP) and has been tested in Western Blotting and Immunohistochemistry.
    主要应用
    • Western Blotting
    应用说明 Immunohistochemistry Analysis: A 1:5000 dilution from a representative lot detected C9RANT (poly-GP) in human cerebellar sections of c9FTD cases (Ash, PE, et al. (2013). Neuron. 77(4):639-646.).
    生物信息
    免疫原品种 Linear peptides corresponding to C-Ahx-(GA)8-amide, C-Ahx-(GP)8-amide, and C-Ahx-
    (GR)8-amide
    表位 poly-GP
    浓缩 Please refer to lot specific datasheet.
    宿主 Rabbit
    品种反应性 Human
    Species Reactivity Note Human. Predicted to react with all species.
    抗体类型 Polyclonal Antibody
    纯化方法 Unpurified
    产品使用声明
    质量保证 Evaluated by Western Blotting in transfected HEK293 cell lysate.

    Western Blotting Analysis: 1:2000 diultion of this antibody detected GST fusion protein with 5 GP repeats in 10 µg of transfected HEK293 cell lysate.
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Stable for 1 year at -20°C from date of receipt.
    Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
    包装信息
    数量 50 µL

    merck millipore,默克密理博,ABN455,Anti-C9ORF72/C9RANT (poly-GP) Antibody

上一件merck millipore产品:merck millipore,默克密理博,110145,D-erythro-Sphingosine, N-Acetyl- - CAS 3102-57-6 - Calbiochem
下一件merck millipore产品:merck millipore,默克密理博,MABC644,Anti-PLAP Antibody, clone EPR6141, rabbit monoclonal



whatman,沃特曼,nalgene,耐洁,merck millipore,默克密理愽,sartorius,赛多利斯,pall,颇尔
thermo fisher,赛默飞世尔,GE,MN,macherey-nagel,advantec,wheaton,brand,普兰德,welch,airtech


上海羽令过滤器材有限公司版权所有 Copyright ©  www.yl-guolv.com  Powered by 羽令集团—信息技术部