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重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 H WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 ABE454 描述 Anti-IDH Antibody Alternate Names - Oxalosuccinate decarboxylase
- Isocitrate dehydrogenase [NADP] cytoplasmic
- IDH
- Cytosolic NADP-isocitrate dehydrogenase
- IDP
- NADP(+)-specific ICDH
背景信息 Isocitrate dehydrogenase 1 (IDH) is a 46 kDa NADP-dependent enzyme, which catalyzes the decarboxylation of isocitrate into α-ketoglutarate. IDH may also play a role in the prevention of oxidative damage, and the shuttling of proteins to peroxisomes. It is widely reported that mutations in IDH result in multiple forms of gliomas. The Arginine to Serine substitution at amino acid 132 is seen in gliomas, abolishes magnesium binding and alters enzyme activity so that isocitrate is no longer converted to alpha-ketoglutarate but instead alpha-ketoglutarate is converted to R(-)-2-hydroxyglutarate. 产品信息 格式 Affinity Purified 控制 - Human liver tissue lysate
演示 Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. 应用 应用 Anti-IDH Antibody is a highly specific rabbit polyclonal antibody, that targets IDH1 & has been tested in western blotting & IHC (Paraffin). 主要应用 - Western Blotting
应用说明 Immunohistochemistry Analysis: A 1:2,000 dilution from a representative lot detected IDH in human glioma cell tissue. 生物信息 免疫原品种 KLH-conjugated linear peptide corresponding to human IDH near the N-Terminus. 表位 Near N-Terminus 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 特异性 This antibody recognizes IDH near the N-Terminus. 品种反应性 Human Species Reactivity Note Demonstrated to react with Human. Predicted to react with Mouse, Rat, Bovine, Equine, and Rhesus Macaque based on 100% sequence homology. 抗体类型 Polyclonal Antibody Entrez基因编号 - NP_005887
基因符号 - PICD
- IDH1
纯化方法 Affinity purified UniProt编号 - O75874
产品使用声明 质量保证 Evaluated by Western Blotting in human liver tissue lysate.
Western Blotting Analysis: 0.1 µg/mL of this antibody detected IDH in 10 µg of human liver tissue lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
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