merck millipore,默克密理愽
  • merck millipore,默克密理博,681671,Wnt Antagonist II, IWP-2 - CAS 686770-61-6 - Calbiochem

  • merck millipore,默克密理博,681671,Wnt Antagonist II, IWP-2 - CAS 686770-61-6 - Calbiochem

    产品名称：Wnt Antagonist II, IWP-2 - CAS 686770-61-6 - Calbiochem
    产品型号：681671
    The Wnt Antagonist II, IWP-2, also referenced under CAS 686770-61-6, controls the biological activity of Wnt. This small molecule/inhibitor is primarily used for Cancer applications.

    merck millipore,默克密理博,681671,Wnt Antagonist II, IWP-2 - CAS 686770-61-6 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,681671,Wnt Antagonist II, IWP-2 - CAS 686770-61-6 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₂₂H₁₈N₄O₂S₃686770-61-6
    描述
    概述 A cell-permeable benzothiazolyl-acetamide compound that inhibits the cellular Wnt processing and secretion via selective blockage of MBOAT (membrane-bound O-acyltranferase) family member Porcn- (Porcupine) mediated Wnt palmitoylation. IWP-2 does not affect Wnt/β-catenin signaling pathway in general and, unlike IWR-1-endo (Cat. No. 681669), displays no effect against Wnt-stimulated cellular responses. Also available as a 10 mM solution in DMSO (Cat. No. 506072).
    产品目录编号 681671
    品牌系列 Calbiochem®
    同义词 Inhibitor of Wnt Production-2, Wnt Pathway Inhibitor II, Porcn Inhibitor I
    参考
    参考 Chen, B., et al. 2009. Nature Chem. Biol. 5, 100.
    产品信息
    CAS号 686770-61-6
    形式 Off-white solid
    Hill配方 C₂₂H₁₈N₄O₂S₃
    化学配方 C₂₂H₁₈N₄O₂S₃
    Molar Mass 466.6
    生物信息
    纯度 ≥97% by HPLC
    理化信息
    溶解度 DMSO or EtOH
    安全信息
    R相 R: 20/21/22

    Harmful by inhalation, in contact with skin and if swallowed.
    S相 S: 22-24/25-36-45

    Do not breathe dust.
    Avoid contact with skin and eyes.
    Wear suitable protective clothing.
    In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Harmful
    储存 +2°C to +8°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,681671,Wnt Antagonist II, IWP-2 - CAS 686770-61-6 - Calbiochem

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