merck millipore,默克密理博,04-968,Anti-Folr4 (Folate receptor 4) Antibody, clone 5E12.2

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品种反应性	主要应用	宿主	格式	抗体类型
M, H	WB	M	Purified	Monoclonal Antibody

描述
产品目录编号	04-968
描述	Anti-Folr4 (Folate receptor 4) Antibody, clone 5E12.2
Alternate Names	Folate receptor 4 folate receptor 4 (delta) homolog (mouse) folate receptor 4 (delta) homolog
背景信息	Folates are necessary and critical components in the synthesis of proteins and nucleic acids, and have putative roles in the development of both the spinal canal and brain in the early stages of pregnancy (Yamaguchi, 2007). Folate receptor 4 (Folr4) is a recently discovered cell surface receptor for folic acid on T regulatory cells (Tregs). Studies have shown that Folr4 has an integral role in the maintenance of Treg cell function (Arase, 2009). Expression of Folr4 in Tregs is notably high, making it an opportune marker for the study of Treg cells. When studied in conjunction with CD4 and CD25, Folr4 also provides researchers with a marker to distinguish between Tregs and other T cells (Chai, 2008). Tregs are of interest in therapeutic, drug research due to their ability to actively suppress immune responses.

产品信息
格式	Purified
控制	Human thymus tissue lysate
演示	Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.05% sodium azide.

应用
应用	Anti-Folr4 (Folate receptor 4) Antibody, clone 5E12.2 detects level of Folr4 (Folate receptor 4) & has been published & validated for use in WB.
主要应用	Western Blotting
应用说明	Western Blot (SNAP ID) Analysis: 1 µg/mL of this antibody detected Folate receptor 4 (Folr4) in 10 µg of human thymus tissue lysate.

生物信息
免疫原品种	KLH-conjugated linear peptide corresponding to human Folate receptor 4 (Folr4).
表位	Unknown
克隆	5E12.2
浓缩	Please refer to the Certificate of Analysis for the lot-specific concentration.
宿主	Mouse
特异性	This antibody recognizes Folate receptor 4 (Folr4).
同种型	IgG1κ
品种反应性	MouseHuman
Species Reactivity Note	Demonstrated to react with human and mouse.
抗体类型	Monoclonal Antibody
Entrez基因编号	NP_001073955.1
基因符号	FR-delta Folbp3 Folr4
纯化方法	Protein G purfied
UniProt编号	A6ND01
UniProt汇总	SUBCELLULAR LOCATION: Secreted Potential. PTM: Eight disulfide bonds are present Potential. SEQUENCE SIMILARITIES: Belongs to the folate receptor family.

产品使用声明
质量保证	Evaluated by Western Blot in human thymus tissue lysate. Western Blot Analysis: 0.5 µg/mL of this antibody detected Folate receptor 4 (Folr4) in 10 µg of human thymus tissue lysate. A previous lot was shown to detect Folate Receptor 4 in mouse thymus tissue lysate.
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Stable for 1 year at 2-8°C from date of receipt.

包装信息
数量	100 µg

merck millipore,默克密理博,04-968,Anti-Folr4 (Folate receptor 4) Antibody, clone 5E12.2

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