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描述 产品目录编号 14-664M 品牌系列 Upstate
商名 - Upstate
描述 Mnk2 Protein, active, 250 µg 概述 N-terminal 6His-tagged, recombinant, human, full length Mnk2 应用 应用 Active, N-terminal 6His-tagged, recombinant, human, full length Mnk2, for use in Kinase Assays. 主要应用 - Kinase Assay
生物信息 来源 expressed by baculovirus in Sf21 cells 品种 Human 特异活性 For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme. Entrez基因编号 - NM_199054.2
- NM_017572.3
基因符号 - MNK2
- MKNK2
- GPRK7
- Mnk2
蛋白靶 Mnk2 纯化方法 Ni2+/NTA-agarose 靶子系列 CAMK UniProt编号 - Q9HBH9
UniProt汇总 FUNCTION: SwissProt: Q9HBH9 # May play a role in the response to environmental stress and cytokines. Appears to regulate transcription by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7-methylguanosine-containing mRNA cap.
COFACTOR: Magnesium. & Binds 1 zinc ion per subunit.
SIZE: 465 amino acids; 51875 Da
SUBUNIT: Monomer. Interacts with the C-terminal regions of EIF4G1 and EIF4G2. Also binds to dephosphorylated ERK1 and ERK2. Isoform 2 interacts with ESR2.
TISSUE SPECIFICITY: Ubiquitously expressed in all tissues examined. Isoform 2 is expressed at higher levels in the ovary than is isoform 1.
PTM: Dual phosphorylation of Thr-244 and Thr-249 activates the kinase. Phosphorylation of Thr-379 activates the kinase.
SIMILARITY: SwissProt: Q9HBH9 ## Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. & Contains 1 protein kinase domain.产品使用声明 质量保证 routinely evaluated by phosphorylation of MBP (Catalog # 13-104) 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 6 months at -70°C 包装信息 数量 250 µg 包装 Also available in 10 μg size (cat#14-664) and in bulk (cat# 14-664-K).
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