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重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 R, H IHC, WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 ABC826 描述 Anti-BCAS3 Antibody Alternate Names - GAOB1
- Breast carcinoma-amplified sequence 3
背景信息 Breast carcinoma-amplified sequence 3 (BCAS3), also known as GAOB1 is localized to 17q23, a region that is often amplified in breast cancers. Copy number gains at this region have also been reported in other tumors such as brain, lung, liver, testis and bladder. BCAS3 is thought to be an estrogen receptor (ER)-α co-activator that acts through PELP1, another ER-α that in turn activates BCAS3 expression. This may set up a positive feedback loop leading to ER-α signal amplification in the cell which may play a significant role in breast cancer. BCAS3 expression has also been observed in embryonic stem cells and vascular precursors, suggesting that it may also play a role in embryogenesis and tumor angiogenesis. 产品信息 格式 Affinity Purified 演示 Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide. 应用 应用 Anti-BCAS3 Antibody detects level of BCAS3 & has been published & validated for use in BCAS3. 主要应用 - Immunohistochemistry
- Western Blotting
应用说明 Immunohistochemistry Analysis: 5 μg/mL from a representative lot detected BCAS3 in human breast carcinoma tissue. 生物信息 免疫原品种 KLH-conjugated synthetic peptide corresponding to the N-terminus of human BCAS3. 表位 N-terminus 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 品种反应性 RatHuman 抗体类型 Polyclonal Antibody 基因符号 - BCAS3
纯化方法 Antigen Affinity purified UniProt编号 - Q9H6U6
产品使用声明 质量保证 Evaluated by Western Blotting in rat brain tissue lysate.
Western Blotting Analysis: 1 μg/mL of this antibody detected BCAS3 in rat brain tissue lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 150 µL
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