- 当前位置：首页 > >Merck Millipore > 生命科学研究
- 生命科学研究
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 H WB, ELISA Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 07-791 品牌系列 Upstate
商名 - Upstate
描述 Anti-phospho-Src Antibody (Tyr215) Alternate Names - p60-Src
- ASV
- KAT13A
- SRC1
- c-SRC
产品信息 格式 Affinity Purified 演示 100 μL of epitope specific affinity purified rabbit polyclonal IgG in 50% affinity storage buffer (PBS containing 1.0 mg/mL BSA and 0.05% sodium azide) and 50% glycerol. 应用 应用 Anti-Src (Tyr215) Antibody is an antibody against Src (Tyr215) for use in ELISA & WB. 主要应用 - Western Blotting
- ELISA
生物信息 免疫原品种 KLH conjugated peptide corresponding to amino acid region encompassing the phosphorylated Tyr215 residue in human c-Src. 宿主 Rabbit 特异性 Recognizes phospho-Src (Tyr215). This peptide sequence is somewhat conserved in other Src family kinases, such as fyn, csk, hck, and yes, and may cross-react when phosphorylated in their corresponding regions. 同种型 IgG 品种反应性 Human Species Reactivity Note Predicted to cross react with other species, but has not been tested. 抗体类型 Polyclonal Antibody Entrez基因编号 - NM_198291.1
- NM_005417.3
Entrez基因汇总 This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene. 基因符号 - pp60c-src
- SRC
- ASV
- c-src
- p60-Src
- SRC1
- c-SRC
纯化方法 Immunoaffinity purified UniProt编号 - P12931
UniProt汇总 SIZE: 536 amino acids; 59835 Da
SUBUNIT: Interacts with DDEF1/ASAP1 via its SH3 domain. Interacts with CCPG1 (By similarity). Interacts with CDCP1, PELP1, TGFB1I1 and TOM1L2.
PTM: Phosphorylated on Tyr-530 by c-Src kinase (CSK). The phosphorylated form is termed pp60c-src. The phosphorylated tail interacts with the SH2 domain thereby repressing kinase activity.
SIMILARITY: SwissProt: P12931 ## Belongs to the protein kinase superfamily. Tyr protein kinase family. SRC subfamily. & Contains 1 protein kinase domain. & Contains 1 SH2 domain. & Contains 1 SH3 domain.产品使用声明 质量保证 Routinely evaluated by immunoblot. 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 2 years at -20°C from date of shipment. Upon first thaw, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerol-containing solutions to become frozen during storage. 包装信息 数量 100 µL
上一件merck millipore产品：merck millipore,默克密理博,AG400,BLACK-GOLD II Stain
下一件merck millipore产品：merck millipore,默克密理博,ABC826,Anti-BCAS3 Antibody
相关产品
merck millipore,默克密理博,07-1233,Anti-Notch 2 Antibody, intracellular
merck millipore,默克密理博,MAB4130,Anti-Thymidylate Synthase Antibody, clone TS106
merck millipore,默克密理博,SF-1298,GDF3; Human, Cyanine 3 RNA Detection Probe,SmartFlare
merck millipore,默克密理博,ABC83,Anti-Angptl3 Antibody
merck millipore,默克密理博,AG400,BLACK-GOLD II Stain
merck millipore,默克密理博,ABC826,Anti-BCAS3 Antibody
merck millipore,默克密理博,20-180,pNPP Tyr Assay Buffer
merck millipore,默克密理博,72622,NovaCHOice Transfection Kit
