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merck millipore,默克密理博,AB9303,Anti-Trace Amine Receptor 1 Antibody
产品名称：Anti-Trace Amine Receptor 1 Antibody
产品型号：AB9303
Anti-Trace Amine Receptor 1 Antibody detects level of Trace Amine Receptor 1 & has been published & validated for use in IH(P) & WB.
merck millipore,默克密理博,AB9303,Anti-Trace Amine Receptor 1 Antibody
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 R, H, Mk WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 AB9303 品牌系列 Chemicon®
商名 - Chemicon
描述 Anti-Trace Amine Receptor 1 Antibody Alternate Names - TA1, TAAR1
- TA1
产品信息 格式 Affinity Purified 演示 Affinity purified immunoglobulin. Liquid in PBS, pH 7.7 with 0.01% sodium azide. 应用 应用 Anti-Trace Amine Receptor 1 Antibody detects level of Trace Amine Receptor 1 & has been published & validated for use in IH(P) & WB. 主要应用 - Western Blotting
应用说明 Immunohistochemistry on paraffin embedded tissue sections.
Western blot.
Optimal working dilutions must be determined by the end user.生物信息 免疫原品种 Synthetic peptide from the 3rd cytoplasmic domain of human Trace Amine Receptor 1. 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 特异性 Recognizes Trace Amine Receptor 1 [TAAR1, TA1]. 品种反应性 RatHumanMonkey Species Reactivity Note The immunogen has 63% similarity with mouse. 抗体类型 Polyclonal Antibody Entrez基因编号 - NM_138327.1
Entrez基因汇总 TAAR1 is a G protein-coupled receptor activated by trace amines. Trace amines are endogenous amine compounds that account for less than 1% of the biogenic amines in most brain regions (Bunzow et al., 2001 [PubMed 11723224]).[supplied by OMIM] 基因符号 - TAR1
- TAAR1
- TA1
- TRAR1
- TaR-1
- MGC138399
- RP11-295F4.9
- MGC126874
UniProt编号 - Q96RJ0
UniProt汇总 FUNCTION: SwissProt: Q96RJ0 # Receptor for trace amines, including beta- phenylethylamine (b-PEA), p-tyramine (p-TYR), octopamine and tryptamine, with highest affinity for b-PEA and p-TYR. Unresponsive to classical biogenic amines, such as epinephrine and histamine and only partially activated by dopamine and serotonine. Trace amines are biogenic amines present in very low levels in mammalian tissues. Although some trace amines have clearly defined roles as neurotransmitters in invertebrates, the extent to which they function as true neurotransmitters in vertebrates has remained speculative. Trace amines are likely to be involved in a variety of physiological functions that have yet to be fully understood. The signal transduced by this receptor is mediated by the G(s)-class of G-proteins which activate adenylate cyclase.
SIZE: 339 amino acids; 39092 Da
SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
TISSUE SPECIFICITY: Detected in low levels in discrete regions within the central nervous system and in several peripheral tissues. Moderately expressed in stomach. Low levels in amygdala, kidney, and lung, and small intestin. Trace amounts in cerebellum, dorsal root ganglia, hippocampus, hypothalamus, liver, medulla, pancreas, pituitary, pontine reticular formation, prostate, skeletal muscle, and spleen.
SIMILARITY: SwissProt: Q96RJ0 ## Belongs to the G-protein coupled receptor 1 family.产品使用声明 销售限制 This product is not available for sale in Japan. 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Maintain at -70°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles. 包装信息 数量 50 µg
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