merck millipore,默克密理愽
  • merck millipore,默克密理博,AB5638P,Anti-Cannabinoid Receptor 1 Antibody, CT

  • merck millipore,默克密理博,AB5638P,Anti-Cannabinoid Receptor 1 Antibody, CT

    产品名称：Anti-Cannabinoid Receptor 1 Antibody, CT
    产品型号：AB5638P
    Anti-Cannabinoid Receptor 1 Antibody, C-terminus is an antibody against Cannabinoid Receptor 1 for use in ELISA & WB.

    merck millipore,默克密理博,AB5638P,Anti-Cannabinoid Receptor 1 Antibody, CT

  • 产品介绍
  • merck millipore,默克密理博,AB5638P,Anti-Cannabinoid Receptor 1 Antibody, CT

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    R, MWB, ELISARbAffinity PurifiedPolyclonal Antibody
    描述
    产品目录编号 AB5638P
    品牌系列 Chemicon®
    商名
    • Chemicon
    描述 Anti-Cannabinoid Receptor 1 Antibody, CT
    Alternate Names
    • CB1
    背景信息 CB1 is a protein that is one of two cannabinoid receptors (CB1 CB2). Cannabinoid principally delta-9-tetrahydrocannabinol (THC) and its synthetic analogs, are the active psychoactive compounds present is marijuana. These cannabinoid receptors are members of the guanine-nucleotide-binding protein (G-protein) coupled receptors which inhibit adenylate cyclase activity in a dose-dependent, stereoselective and pertussis toxin-sensitive manner. The two receptors have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. Three splice variants have been found for this gene. CB1 is primarily located in brain, and CB2 is found macrophages.
    产品信息
    格式 Affinity Purified
    演示 Affinity purified immunoglobulin. Liquid in phosphate buffered saline, pH 7.4, containing 0.1% BSA.
    应用
    应用 Anti-Cannabinoid Receptor 1 Antibody, C-terminus is an antibody against Cannabinoid Receptor 1 for use in ELISA & WB.
    主要应用
    • Western Blotting
    • ELISA
    应用说明 Western blot: 1-10 μg/mL using ECL. Expected sizes are ~60kDa and 80-84kDa under reducing conditions.

    Immunohistochemistry: not tested. It is recommended that the antibody be tried at 2-10 μg/mL on paraformaldehyde fixed tissue.

    ELISA: 1:10,000-1:100,000 using 50-100 ng control peptide (Catalog number AG213) per well.

    Optimal working dilutions must be determined by the end user.
    生物信息
    免疫原品种 A 20 amino acid peptide sequence near the cytoplasmic, C-terminus of rat CB1 (Gerard et al. 1991; Gerard et al.

    1990; Shire et al. 1995; Matsuda et al. 1990; Ho et al. 1996; Chakraborty et al. 1995).
    表位 C-terminus
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Rabbit
    特异性 Recognizes rat Cannabinoid Receptor 1 (CB1). The immunogen shows no significant sequence homology with CB2 or other receptors.

    SPECIES REACTIVITIES: The immunogen peptide is 100% conserved mouse, 94% in monkey and human, 88% in zebra finch, 75% in feline and newt, (salamander) and 73% in puffer fish. Reactivity with other species has not been confirmed.
    品种反应性 RatMouse
    抗体类型 Polyclonal Antibody
    Entrez基因编号
    • NM_033181.2
    • NM_016083.3
    Entrez基因汇总 This gene encodes a protein that is one of two cannabinoid receptors. The cannabinoids, principally delta-9-tetrahydrocannabinol and synthetic analogs, are psychoactive ingredients of marijuana. The cannabinoid receptors are members of the family of guanine-nucleotide-binding protein (G-protein) coupled receptors which inhibit adenylate cyclase activity in a dose-dependent, stereoselective and pertussis toxin-sensitive manner. The two receptors have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. Two transcript variants encoding different isoforms have been described for this gene.
    基因符号
    • CB-R
    • CNR1
    • CNR
    • CANN6
    • CB1A
    • CB1
    • CB1K5
    UniProt编号
    • P21554
    UniProt汇总 FUNCTION: SwissProt: P21554 # Involved in cannabinoid-induced CNS effects. Acts by inhibiting adenylate cyclase. Could be a receptor for anandamide. Isoform 2 and isoform 3 have altered ligand binding.
    SIZE: 472 amino acids; 52858 Da
    SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
    TISSUE SPECIFICITY: Widely expressed.
    SIMILARITY: SwissProt: P21554 ## Belongs to the G-protein coupled receptor 1 family.
    产品使用声明
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Maintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles.
    包装信息
    数量 50 µg

    merck millipore,默克密理博,AB5638P,Anti-Cannabinoid Receptor 1 Antibody, CT

上一件merck millipore产品：merck millipore,默克密理博,06-1340,Anti-phospho-IKK-epsilon (Ser172) Antibody
下一件merck millipore产品：merck millipore,默克密理博,ABE582,Anti-HEXIM1 Antibody


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