• merck millipore,默克密理博,616387,Nα-Tosyl-Phe Chloromethyl Ketone
  • merck millipore,默克密理博,616387,Nα-Tosyl-Phe Chloromethyl Ketone

    产品名称:Nα-Tosyl-Phe Chloromethyl Ketone
    产品型号:616387
    Irreversible inhibitor of chymotrypsin.

    merck millipore,默克密理博,616387,Nα-Tosyl-Phe Chloromethyl Ketone

  • 产品介绍
  • merck millipore,默克密理博,616387,Nα-Tosyl-Phe Chloromethyl Ketone

    重要规格表

    经验配方 CAS号
    C₁₇H₁₈ClNO₃S402-71-1
    描述
    概述

    This product has been discontinued.



    Irreversible inhibitor of chymotrypsin. Useful for inhibiting chymotrypsin activity in trypsin preparations. Inhibits apoptosis in thymocytes. Blocks the induction of nitric oxide synthase by γ-interferon and lipopolysaccharides (EC50 = 20 µM).
    产品目录编号 616387
    品牌系列 Calbiochem®
    同义词 TPCK
    参考
    参考 Fearnhead, H.O., et al. 1995. FEBS Lett. 357, 242.
    Griscavage, J.M., et al. 1995. Biochem. Biophys. Res. Commun. 215, 721.
    Weaver, V.M., et al. 1993. Biochem. Cell Biol. 71, 488.
    Murakami, T., et al. 1991. Biochim. Biophys. Acta 1079, 279.
    Nierodzik, M.L., et al. 1991. J. Clin. Invest. 87, 229.
    Wilson, W.E., et al. 1989. J. Biol. Chem. 264, 17777.
    产品信息
    CAS号 402-71-1
    具有ATP竞争性 N
    形式 White solid
    Hill配方 C₁₇H₁₈ClNO₃S
    化学配方 C₁₇H₁₈ClNO₃S
    Molar Mass 351.5
    可逆 N
    结构配方图像
    生物信息
    主靶 chymotrypsin activity in preparations
    主靶IC50 EC50 = 20 µM in blocking the induction of nitric oxide synthase by γ-interferon and lipopolysaccharides.
    纯度 ≥98% by TLC
    理化信息
    细胞可渗透 N
    溶解度 EtOH or MeOH
    GHS安全信息
    RTECS XT5613500
    安全信息
    R相 R: 41

    Risk of serious damage to eyes.
    S相 S: 26-36

    In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
    Wear suitable protective clothing.
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Irritant
    储存 +2°C to +8°C
    无需冷冻 No
    特殊指南 Following reconstitution, store in the refrigerator (4°C). Stock solutions are stable for up to 4 months at 4°C.

    merck millipore,默克密理博,616387,Nα-Tosyl-Phe Chloromethyl Ketone

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