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merck millipore,默克密理博,AB5423,Anti-Tyrosine Hydroxylase Antibody, phosphoSer31
产品名称：Anti-Tyrosine Hydroxylase Antibody, phosphoSer31
产品型号：AB5423
This Anti-Tyrosine Hydroxylase Antibody, phosphoSer31 is validated for use in IC, IH, WB for the detection of Tyrosine Hydroxylase.
merck millipore,默克密理博,AB5423,Anti-Tyrosine Hydroxylase Antibody, phosphoSer31
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 R WB, ICC, IHC Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 AB5423 品牌系列 Chemicon®
商名 - Chemicon
描述 Anti-Tyrosine Hydroxylase Antibody, phosphoSer31 产品信息 格式 Affinity Purified 演示 Affinity purified immunoglobulin. Liquid in 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50% glycerol. 应用 应用 This Anti-Tyrosine Hydroxylase Antibody, phosphoSer31 is validated for use in IC, IH, WB for the detection of Tyrosine Hydroxylase. 主要应用 - Western Blotting
- Immunocytochemistry
- Immunohistochemistry
应用说明 Western blot: 1:1,000
Immunocytochemistry: 1:1,000
Immunohistochemistry: 1:1,000
Optimal working dilutions must be determined by the end user.生物信息 免疫原品种 Synthetic peptide from the phosphoSer31 of rat Tyrosine Hydroxylase. Available as catalog number AG398 表位 phosphoSer31 宿主 Rabbit 特异性 Tyrosine Hydroxylase, phosphoSer31. The antibody recognizes a protein of 60 kDa corresponding to TH phosphorylated at Ser31 in lysates of PC-12 cells stimulated by okadaic acid. 品种反应性 Rat 抗体类型 Polyclonal Antibody Entrez基因编号 - NM_199293.2
- NM_000360.3
- NM_199292.2
Entrez基因汇总 Tyrosine hydroxylase is involved in the conversion of tyrosine to dopamine. As the rate-limiting enzyme in the synthesis of catecholamines, tyrosine hydroxylase has a key role in the physiology of adrenergic neurons. 基因符号 - EC 1.14.16.2
- TH
- TYH
修改 - Phosphorylation
UniProt编号 - P07101
UniProt汇总 FUNCTION: SwissProt: P07101 # Plays an important role in the physiology of adrenergic neurons.
COFACTOR: Fe(2+) ion.
SIZE: 528 amino acids; 58524 Da
TISSUE SPECIFICITY: Mainly expressed in the brain and adrenal glands.
DISEASE: SwissProt: P07101 # Defects in TH are the cause of autosomal recessive Segawa syndrome [MIM:605407]; also known as DOPA-responsive dystonia. Typically, it begins in childhood or adolescence with progressive difficulty in walking and, in some cases, spasticity. Some cases present with parkinsonian symptoms in infancy and are referred to as autosomal recessive infantile parkinsonism.
SIMILARITY: SwissProt: P07101 ## Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Maintain at -20°C in undiluted for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles. Do not store in a self defrosting freezer. 包装信息 数量 100 µL
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下一件merck millipore产品：merck millipore,默克密理博,345795,β1,3-Galactosidase, Xanthomonas manihotis, Recombinant, E. coli
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