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品种反应性 主要应用 宿主 格式 抗体类型 Ma IHC, ELISA, WB, ICC Rb Serum Polyclonal Antibody 描述 产品目录编号 AB5354 Replaces 04-1032 品牌系列 Chemicon®
商名 - Chemicon
描述 Anti-Internexin α Antibody 产品信息 格式 Serum 控制 - POSITIVE CONTROL CELLS: PC12, Ntera2.
演示 Serum liquid, containing no preservatives. 应用 应用 Anti-Internexin Antibody, α is an antibody against Internexin for use in ELISA, WB, IC, IH. 主要应用 - Immunohistochemistry
- ELISA
- Western Blotting
- Immunocytochemistry
应用说明 Immunohistochemistry on formalin or paraformaldehyde fixed tissues.
Immunocytochemistry.
Western blot: using human or rat brain homogenates.
ELISA
Optimal working dilutions must be determined by end user.生物信息 免疫原品种 Full length recombinant rat alpha-internexin fused to E. coli Trp E. 宿主 Rabbit 特异性 alpha-internexin, C-terminal globular "tail" region. By western blot, AB5354 detects a major band at 66 kDa and a minor band at approximately 150 kDa corresponding to alpha internexin monomer and dimer, respectively. A minor band at approximately 50 kDa is occasionally detected and is believed to be a degradation product of alpha internexin. This antibody has been referred to in the literature as the R36 antibody (Evans, 2002). 品种反应性 Mammals 抗体类型 Polyclonal Antibody Entrez基因编号 - NM_032727.2
基因符号 - Alpha-internexin
- INA
- NF-66
- NEF5
- MGC12702
- Alpha-Inx
- TXBP-1
- Neurofilament-66
UniProt编号 - Q16352
UniProt汇总 FUNCTION: SwissProt: Q16352 # Class-IV neuronal intermediate filament that is able to self-assemble. It is involved in the morphogenesis of neurons. It may form an independent structural network without the involvement of other neurofilaments or it may cooperate with NF-L to form the filamentous backbone to which NF-M and NF-H attach to form the cross-bridges.
SIZE: 499 amino acids; 55391 Da
TISSUE SPECIFICITY: Found predominantly in adult CNS.
DEVELOPMENTAL STAGE: Expressed in brain as early as the 16th week of gestation, and increased rapidly and reached a steady state level by the 18th week of gestation.
PTM: O-glycosylated (By similarity). & Phosphorylated upon DNA damage, probably by ATM or ATR.
SIMILARITY: SwissProt: Q16352 ## Belongs to the intermediate filament family.产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Maintain frozen at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles. 包装信息 数量 50 µL
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