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品种反应性 主要应用 宿主 格式 抗体类型 Chp, H, M FC, IHC, ELISA Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 06-1080 描述 Anti-IL-25 (IL-17E) Antibody, NT Alternate Names - interleukin 25
- interleukin 17E
背景信息 Interleukin-25 (IL-25 or IL-17E) is a cytokine that belongs to the IL-17 cytokine family secreted by type 2 helper T cells (Th2) and mast cells. As an inducer of other cytokines, including IL-4, IL-5 and IL-13 in multiple tissues, IL-25 helps stimulate the expansion of eosinophils. This cytokine is an important molecule controlling immunity of the gastrointestinal tract and has been implicated in chronic inflammation associated with this area of the body. 产品信息 格式 Affinity Purified 控制 - Mouse testis tissue
演示 Purified rabbit polyclonal in PBS with 0.05% sodium azide. 应用 应用 Detect IL-25 (IL-17E) using this Anti-IL-25 (IL-17E) Antibody, N-terminus validated for use in IH, ELISA, FC. 主要应用 - Flow Cytometry
- Immunohistochemistry
- ELISA
应用说明 Flow Cytometry Analysis: 5 µg from a previous lot was used to detect IL-25 in HeLa cells.
ELISA: A previous lot of this antibody was used in ELISA by an independent laboratory.生物信息 免疫原品种 KLH-conjugated linear peptide corresponding to human IL-25 at and around the N-terminus. 表位 N-terminus 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 特异性 This antibody recognizes IL-25 at the N-terminus. 品种反应性 ChimpanzeeHumanMouse Species Reactivity Note Proven to react with human and mouse.
Predicted to react with chimpanzee based on 100% sequence homology.抗体类型 Polyclonal Antibody Entrez基因编号 - NP_073626
Entrez基因汇总 The protein encoded by this gene is a cytokine that shares sequence similarity with IL17. This cytokine can induce NF-kappaB activation, and stimulate the production of IL8. Both this cytokine and IL17B are ligands for the cytokine receptor IL17BR. Studies of similar genes in mice suggested that this cytokine may be a proinflammatory cytokine favoring Th2-type immune response. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq] 基因符号 - Interleukin-17E
- IL25
- IL-17E
- IL-25
- IL17E
纯化方法 Affinity Purfied UniProt编号 - Q9H293
UniProt汇总 FUNCTION: Induces activation of NF-kappa-B and stimulates production of the proinflammatory chemokine IL-8. Proinflammatory cytokine favoring Th2-type immune responses.
SUBCELLULAR LOCATION: Secreted.
TISSUE SPECIFICTY: Expressed at low levels in several tissues, including brain, kidney, lung, prostate, testis, spinal cord, adrenal gland, and trachea.
SEQUENCE SIMILARITIES: Belongs to the IL-17 family.产品使用声明 质量保证 Evaluated by Immunohistochemistry in mouse testis tissue.
Immunohistochemistry Analysis: 1:50-300 dilution of this antibody detected IL-25 in mouse testis tissue.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
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