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merck millipore,默克密理博,AB3468,Anti-Heat Shock Protein 90β Antibody
产品名称:Anti-Heat Shock Protein 90β Antibody
产品型号:AB3468
This Anti-Heat Shock Protein 90β Antibody is validated for use in IP, WB, IC, IH(P) for the detection of Heat Shock Protein 90β.
merck millipore,默克密理博,AB3468,Anti-Heat Shock Protein 90β Antibody
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 R, H, M ICC, WB Rb Purified Polyclonal Antibody 描述 产品目录编号 AB3468 品牌系列 Chemicon®
商名 - Chemicon
描述 Anti-Heat Shock Protein 90β Antibody Alternate Names - HSP84
产品信息 格式 Purified 控制 - POSITIVE CONTROL: MAD109 cells or breast carcinoma.
演示 Purified immunoglobulin. Liquid in 10 mM PBS, pH 7.4 with 0.2% BSA and 15 mM sodium azide. 应用 应用 This Anti-Heat Shock Protein 90β Antibody is validated for use in IP, WB, IC, IH(P) for the detection of Heat Shock Protein 90β. 主要应用 - Immunocytochemistry
- Western Blotting
应用说明 Immunoblotting: 5 μg/mL
Immunohistochemistry (frozen and formalin/paraffin): 5-10 μg/mL. Staining of formalin fixed tissue sections requires boiling the tissue sections in 10mM citrate buffer, pH 6.0 for 10-20 minutes followed by cooling at room temperature for 20 minutes.
Immunocytochemistry
Immunoprecpitation: 10 μg/mg of protein lysate.
Optimal working dilutions must be determined by end user.生物信息 免疫原品种 Synthetic peptide corresponding to amino acids 2-13 from the N-terminus of mouse heat shock protein 90b. 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 特异性 Reacts with a protein of 84 kD identified as heat shock protein 90beta (HSP90beta). No reactivity with HSP90alpha/HSP86.
CELLULAR LOCALIZATION: Nuclear and Cytoplasmic.品种反应性 RatHumanMouse 抗体类型 Polyclonal Antibody Entrez基因编号 - NM_007355.2
基因符号 - HSP90-BETA
- HSPC2
- FLJ26984
- D6S182
- HSP90B
- OTTHUMP00000039869
- HSPCB
- HSP90AB1
UniProt编号 - P08238
UniProt汇总 FUNCTION: SwissProt: P08238 # Molecular chaperone. Has ATPase activity.
SIZE: 724 amino acids; 83264 Da
SUBUNIT: Homodimer. Interacts with TP53/p53 (By similarity). Interacts with UNC45A. Binding to UNC45A involves 2 UNC45A monomers per HSP90AB1 dimer.
SUBCELLULAR LOCATION: Cytoplasm. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
PTM: Phosphorylated upon DNA damage, probably by ATM or ATR.
SIMILARITY: SwissProt: P08238 ## Belongs to the heat shock protein 90 family.产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Maintain at 2-8°C in undiluted aliquots for up to 6 months. 包装信息 数量 500 µL
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