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  • merck millipore,默克密理博,AB2261,Anti-Tbr1 Antibody

  • merck millipore,默克密理博,AB2261,Anti-Tbr1 Antibody

    产品名称：Anti-Tbr1 Antibody
    产品型号：AB2261
    Anti-Tbr1 Antibody is an antibody against Tbr1 for use in WB, IH.

    merck millipore,默克密理博,AB2261,Anti-Tbr1 Antibody

  • 产品介绍
  • merck millipore,默克密理博,AB2261,Anti-Tbr1 Antibody

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    Ca, H, M, R, Eq, Po, Op, BIHC, WBChAffinity PurifiedPolyclonal Antibody
    描述
    产品目录编号 AB2261
    描述 Anti-Tbr1 Antibody
    Alternate Names
    • T-box, brain, 1
    背景信息 Tbr1 gene is a member of a conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. Tbr1, a putative transcription factor known to be expressed in post-mitotic neurons, has been found highly expressed in glutamatergic early-born cortical neurons. A similar protein has been disrupted in mice and shown to be critical for early cortical development, and causes loss of projection neurons in the olfactory bulbs and olfactory cortex. The C-terminal region the Tbr1 derived protein was found to be necessary and sufficient for association with the guanylate kinase domain of calcium/calmodulin-dependent serine protein kinase.
    产品信息
    格式 Affinity Purified
    控制
    • Human fetal brain tissue lysate
    演示 Purified chicken polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.05% sodium azide.
    应用
    应用 Anti-Tbr1 Antibody is an antibody against Tbr1 for use in WB, IH.
    主要应用
    • Immunohistochemistry
    • Western Blotting
    应用说明 Immunohistochemistry Analysis: 1:100 dilution from a previous lot detected Tbr1 in mouse frontal cortex tissue.
    生物信息
    免疫原品种 KLH-conjugated linear peptide corresponding to mouse Tbr1.
    表位 Internal
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Chicken
    特异性 This antibody recognizes Tbr1.
    品种反应性 CanineHumanMouseRatHorsePigOpossumBovine
    Species Reactivity Note Proven to react with human, mouse, and rat. Predicted to react with horse, pig, opossum, bovine, and canine based on 100% sequence homology.
    抗体类型 Polyclonal Antibody
    Entrez基因编号
    • NP_033348
    基因符号
    • TES-56
    • Tbr1
    • T-brain-1
    • TBR-1
    纯化方法 Affinity Purfied
    UniProt编号
    • Q64336
    UniProt汇总 FUNCTION: Probable transcriptional regulator involved in developmental processes. TBR1 is required for normal brain development.

    SUBCELLULAR LOCATION: Nucleus Potential.

    TISSUE SPECIFICTY: Expressed in specific lamina in the developing and adult brain.

    DEVELOPMENTAL STAGE: First detected around day 10 of embryonic development in the preplate, at day 12.5, in the cortical plate and intermediate zone, and from day 16.5 to 18.5, in a rostro-caudal gradient in the subplate. In the thalamus, expression is first observed at postnatal stage, P7, and weak expression continues in later postnatal and adult stages.

    SEQUENCE SIMILARITIES: Contains 1 T-box DNA-binding domain.
    产品使用声明
    质量保证 Evaluated by Western Blot in human fetal brain tissue lysate.

    Western Blot Analysis: 0.025 µg/ml of this antibody detected Tbr1 on 10 µg of human fetal brain tissue lysate.
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Stable for 1 year at 2-8°C from date of receipt.
    包装信息
    数量 100 µg

    merck millipore,默克密理博,AB2261,Anti-Tbr1 Antibody

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