merck millipore,默克密理愽
  • merck millipore,默克密理博,219415,Cathepsin Inhibitor I - Calbiochem

  • merck millipore,默克密理博,219415,Cathepsin Inhibitor I - Calbiochem

    产品名称：Cathepsin Inhibitor I - Calbiochem
    产品型号：219415
    The Cathepsin Inhibitor I controls the biological activity of Cathepsin. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.

    merck millipore,默克密理博,219415,Cathepsin Inhibitor I - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,219415,Cathepsin Inhibitor I - Calbiochem

    重要规格表

    经验配方
    C₂₆H₂₅N₃O₆
    描述
    概述 Cell-permeable cysteine protease inhibitor. Inhibits cathepsin B (k2/Ki = 8.9 x 103 M-1 sec-1), cathepsin L (k2/Ki = 3.8 x 105 M-1 sec-1), cathepsin S (k2/Ki = 4.2 x 104 M-1 sec-1), and papain (k2/Ki = 2.4 x 103 M-1 sec-1).
    Half-life in buffered solution (pH 5-9) = 25 h (30°C); 300 h (0°C).
    产品目录编号 219415
    品牌系列 Calbiochem®
    同义词 Z-FG-NHO-Bz, CATI -1
    参考
    参考 Zhu, D. and Uckun, F.M. 2000. Clin. Cancer Res. 6, 2064.
    Demuth, H.-U., et al. 1996. Biochim. Biophys. Acta 1295, 179.
    Brömme, D., and Demuth, H.-U. 1994. Methods Enzymol. 244, 671.
    产品信息
    具有ATP竞争性 N
    形式 White solid
    Hill配方 C₂₆H₂₅N₃O₆
    化学配方 C₂₆H₂₅N₃O₆
    Molar Mass 475.5
    肽序列 Z-Phe-Gly-NHO-Bz
    可逆 N
    结构配方图像
    生物信息
    主靶 cathepsin B
    主靶Ki k₂/Ki = 8.9 x 10³ M⁻¹sec⁻¹ for cathepsin B
    纯度 >90% by HPLC
    理化信息
    细胞可渗透 Y
    溶解度 DMSO or EtOH
    肽序列 Z-Phe-Gly-NHO-Bz
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 +15°C to +30°C
    避光 Protect from light
    防潮 Protect from moisture
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

    merck millipore,默克密理博,219415,Cathepsin Inhibitor I - Calbiochem

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