merck millipore,默克密理愽
  • merck millipore,默克密理博,553031,RAGE Antagonist Peptide, RAP - Calbiochem

  • merck millipore,默克密理博,553031,RAGE Antagonist Peptide, RAP - Calbiochem

    产品名称：RAGE Antagonist Peptide, RAP - Calbiochem
    产品型号：553031
    The RAGE Antagonist Peptide, RAP controls the biological activity of RAGE.

    merck millipore,默克密理博,553031,RAGE Antagonist Peptide, RAP - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,553031,RAGE Antagonist Peptide, RAP - Calbiochem

    重要规格表

    经验配方
    C₅₇H₁₀₁N₁₃O₁₇S
    描述
    概述 An S100P-derived peptide based competitive antagonist for receptor for advanced glycation end product (RAGE). Shown to disrupt the interaction between RAGE and its ligands, such as S100P, S100A4 and HMGB-1 in binding assays and in multiple cancer cell lines (~2 µM). Also, blocks RAGE-dependent NF-kB activation in MPanc96, MOH and HPAF II tumor cell lines. Systemic administration of RAP also diminishes NF-kB signaling in vivo and significantly reduces glioma tumor growth in murine models.
    产品目录编号 553031
    品牌系列 Calbiochem®
    同义词 ELKVLMEKEL
    参考
    参考 Arumugam, T., et al. 2012. Clin Cancer Res. 18, 4356.
    产品信息
    形式 White powder
    配方 Supplied as a trifluoroacetate salt.
    Hill配方 C₅₇H₁₀₁N₁₃O₁₇S
    Molar Mass 1272.6
    肽序列 Ac-ELKVLMEKEL-NH2
    可逆 Y
    生物信息
    主靶 RAGE
    主靶IC50 2 µ
    纯度 ≥95% by HPLC
    理化信息
    溶解度 H₂O
    肽序列 Ac-ELKVLMEKEL-NH2
    储存和货运信息
    货运代码 Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
    毒性 Standard Handling
    储存 -20°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,553031,RAGE Antagonist Peptide, RAP - Calbiochem

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