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品种反应性 主要应用 宿主 格式 抗体类型 M WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 AB15794 品牌系列 Chemicon®
商名 - Chemicon
描述 Anti-Dexras1 Antibody Alternate Names - Activator of G-Protein Signaling 1, AGS1
- Activator of G-Protein Signaling 1
背景信息 Dexras1 is a member of the superfamily of RAS-g-proteins and directly binds to Gialpha heterotrimeric G-proteins where it appears to promote guanine nucleotide exchange on Gialpha. Dexras1 is implicated in NMDA receptor signaling through nitric oxide synthase. 产品信息 格式 Affinity Purified 演示 Liquid in PBS. Contains no preservative 应用 应用 This Anti-Dexras1 Antibody is validated for use in WB for the detection of Dexras1. 主要应用 - Western Blotting
应用说明 Western blot: 1:1,000 on mouse brain extract.
Optimal working dilutions must be determined by the end user.生物信息 免疫原品种 Synthetic peptide. 宿主 Rabbit 特异性 Dexras1 (Activator of G-Protein Signaling 1, AGS1). By Western blot the antibody recognizes a band at ~33 kDa on mouse brain extract. The antibody has also been used to detect Dexras1 in brown adipocyte lysate. 品种反应性 Mouse Species Reactivity Note Mouse. Other species have not been tested. The antibody is also expected to react with human and rat due to immunogen sequence homology (100%). 抗体类型 Polyclonal Antibody Entrez基因编号 - NM_016084.3
Entrez基因汇总 This gene encodes a Ras-related protein that is stimulated by dexamethasone. The exact function of this gene is unknown, but it may play a role in dexamethasone-induced alterations in cell morphology, growth and cell-extracellular matrix interactions. In addition, studies of a similar rat protein suggest that it functions as as a novel physiologic nitric oxide (NO) effector. The gene product belongs to the Ras superfamily of small GTPases. 基因符号 - AGS1
- RASD1
- MGC:26290
- DEXRAS1
纯化方法 Immunoaffinity purified UniProt编号 - Q9Y272
UniProt汇总 SIZE: 281 amino acids; 31642 Da
SUBUNIT: Forms a ternary complex with CAPON and NOS1 (By similarity).
SUBCELLULAR LOCATION: Cell membrane; Lipid-anchor; Cytoplasmic side (Potential).
TISSUE SPECIFICITY: Expressed in a variety of tissues including heart, cardiovascular tissues, brain, placenta, lung, liver, skeletal muscle, kidney, pancreas, gastrointestinal and reproductive tissues.
SIMILARITY: SwissProt: Q9Y272 ## Belongs to the small GTPase superfamily. RasD family.产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 6 months at -70°C from date of shipment 包装信息 数量 100 µL
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