merck millipore,默克密理愽
  • merck millipore,默克密理博,AB15408,Anti-APG10 Antibody

  • merck millipore,默克密理博,AB15408,Anti-APG10 Antibody

    产品名称：Anti-APG10 Antibody
    产品型号：AB15408
    Anti-APG10 Antibody detects level of APG10 & has been published & validated for use in WB, IC, IH.

    merck millipore,默克密理博,AB15408,Anti-APG10 Antibody

  • 产品介绍
  • merck millipore,默克密理博,AB15408,Anti-APG10 Antibody

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    HIHC, WB, ICCRbSerumPolyclonal Antibody
    描述
    产品目录编号 AB15408
    品牌系列 Chemicon®
    商名
    • Chemicon
    描述 Anti-APG10 Antibody
    Alternate Names
    • Autophagy-related protein 10, APG10-like, ATG10
    • Autophagy-related protein 10
    • APG10-like
    背景信息 Autophagy is the process by which cells recycle cytoplasm and dispose of excess or defective organelles. This process is suggested to be involved development, differentiation, growth regulation and tissue remodeling in multicellular organisms. The APG10 protein plays a role in the conjugation of APG5 to APG12 and this conjugate is required for elongation of the isolation membrane to form a complete spherical autophagosome. The APG10 is able to interact with MAP1LC3A and with APG5 and APG7.
    产品信息
    格式 Serum
    演示 Lyophilized. Reconstitute with 50 μL of sterile distilled water. Centrifuge to remove any insoluble material. Contains no preservative.
    应用
    应用 Anti-APG10 Antibody detects level of APG10 & has been published & validated for use in WB, IC, IH.
    主要应用
    • Immunohistochemistry
    • Western Blotting
    • Immunocytochemistry
    应用说明 Western blot: 1:200-1:1,000
    Immunocytochemistry: 1:200-1:1,000
    Immunohistochemistry: 1:200-1:1,000
    Optimal working dilutions must be determined by end user.
    生物信息
    免疫原品种 Synthetic peptide corresponding to a region within the C-terminus of human APG10 protein.
    宿主 Rabbit
    特异性 APG10 [Autophagy-related protein 10, APG10-like, ATG10].
    品种反应性 Human
    抗体类型 Polyclonal Antibody
    Entrez基因编号
    • NM_031482.3
    Entrez基因汇总 Autophagy is a process for the bulk degradation of cytosolic compartments by lysosomes. ATG10 is an E2-like enzyme involved in 2 ubiquitin-like modifications essential for autophagosome formation: ATG12 (MIM 609608)-ATG5 (MIM 604261) conjugation and modification of a soluble form of MAP-LC3 (MAP1LC3A; MIM 601242), a homolog of yeast Apg8, to a membrane-bound form (Nemoto et al., 2003 [PubMed 12890687]).[supplied by OMIM]
    基因符号
    • pp12616
    • ATG10
    • APG10
    • DKFZP586I0418
    • APG10L
    • APG10-like
    • ORFNames=PP12616
    • FLJ13954
    纯化方法 Serum
    UniProt编号
    • Q9H0Y0
    UniProt汇总 FUNCTION: SwissProt: Q9H0Y0 # Plays a role in autophagy (By similarity). ATG12- conjugating enzyme (E2-like enzyme), likely serves as an ATG5- recognition molecule.
    SIZE: 220 amino acids; 25279 Da
    SUBUNIT: Interacts with MAP1LC3A. By interacting with MAP1LC3A, it plays a role in the conjugation of ATG12 to ATG5. Also able to directly interact either with ATG5 or ATG7 (By similarity).
    SUBCELLULAR LOCATION: Cytoplasm (Probable).
    SIMILARITY: SwissProt: Q9H0Y0 ## Belongs to the ATG10 family.
    产品使用声明
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Maintain lyophilized material frozen at -20°C to -70°C for up to 12 months after date of receipt. After reconstitution maintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles. Glycerol (1:1, ACS or better grade) can be added for additional stability.
    包装信息
    数量 50 µL

    merck millipore,默克密理博,AB15408,Anti-APG10 Antibody

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