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品种反应性 主要应用 宿主 格式 抗体类型 H WB Rb Serum Polyclonal Antibody 描述 产品目录编号 AB10080 品牌系列 Chemicon®
商名 - Chemicon
描述 Anti-CYP450 Antibody, clone 2E1 Alternate Names - cytochrome P450
产品信息 格式 Serum 演示 Raw Rabbit Serum with 0.1% Sodium Azide 应用 应用 Anti-CYP450 Antibody, clone 2E1 is an antibody against CYP450 for use in WB. 主要应用 - Western Blotting
生物信息 免疫原品种 Recombinant CYP450 2E1 宿主 Rabbit 品种反应性 Human 抗体类型 Polyclonal Antibody Entrez基因编号 - NM_000773.3
Entrez基因汇总 This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is induced by ethanol, the diabetic state, and starvation. The enzyme metabolizes both endogenous substrates, such as ethanol, acetone, and acetal, as well as exogenous substrates including benzene, carbon tetrachloride, ethylene glycol, and nitrosamines which are premutagens found in cigarette smoke. Due to its many substrates, this enzyme may be involved in such varied processes as gluconeogenesis, hepatic cirrhosis, diabetes, and cancer. 基因符号 - CPE1
- CYP2E1
- OTTHUMP00000046571
- CYPIIE1
- CYP2E
- P450C2E
- P450-J
UniProt编号 - P05181
UniProt汇总 FUNCTION: SwissProt: P05181 # Metabolizes several precarcinogens, drugs, and solvents to reactive metabolites. Inactivates a number of drugs and xenobiotics and also bioactivates many xenobiotic substrates to their hepatotoxic or carcinogenic forms.
SIZE: 493 amino acids; 56849 Da
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
SIMILARITY: SwissProt: P05181 ## Belongs to the cytochrome P450 family.产品使用声明 质量保证 Routinely evaluated by immunoblot. 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 1 year at 2-8°C from date of shipment 包装信息 数量 50 µL
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