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merck millipore,默克密理博,AB10002,Anti-mouse BID cleavage (59/60) site specific Antibody
产品名称:Anti-mouse BID cleavage (59/60) site specific Antibody
产品型号:AB10002
This Anti-mouse BID cleavage (59/60) site specific Antibody is validated for use in WB for the detection of mouse BID cleavage (59/60) site specific.
merck millipore,默克密理博,AB10002,Anti-mouse BID cleavage (59/60) site specific Antibody
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 M WB Rb Purified Polyclonal Antibody 描述 产品目录编号 AB10002 品牌系列 Chemicon®
商名 - Chemicon
描述 Anti-mouse BID cleavage (59/60) site specific Antibody 背景信息 BH3 interacting domain death agonist (BID, 22 kDa) is a pro-apoptotic member of the Bcl-2 family. BID interacts with both Bcl-2 and Bax through its BH3 domain. It usually exists in an inactive form in the cytosolic fraction of living cells and becomes cleaved and activated by caspase-8 in response to TNF-α or Fas ligand. Once BID is cleaved, the C-terminal 15 kDa fragment of BID translocates onto mitochondria and is sufficient to trigger cytochrome c release, resulting in cell apoptosis. BID serves as a direct molecular link between caspase-8 activation and mitochondrial death machinery. 产品信息 格式 Purified 控制 - Mouse L929 (3T3-L1) cells treated with TNF-α to induce cleavage; caspase-8 cleaved recombinant mouse BID.
演示 Dulbecco's phosphate buffered saline (without Mg2+ and Ca2+), pH 7.3 (+/- 0.1), 50% glycerol with 1.0 mg/mL BSA (IgG, protease free) as a carrier, 0.05% sodium azide. 应用 应用 This Anti-mouse BID cleavage (59/60) site specific Antibody is validated for use in WB for the detection of mouse BID cleavage (59/60) site specific. 主要应用 - Western Blotting
生物信息 免疫原品种 The antiserum was produced against a chemically synthesized peptide derived from the 15 kDa caspase-8 cleavage product of mouse BID. 宿主 Rabbit 特异性 Mouse 15 kDa caspase-8 cleavage product of BID. Human (75% conserved) BID has been tested and shown not to cross-react. Rat (100% conserved) and chicken (62% conserved) BID have not been tested. 品种反应性 Mouse 抗体类型 Polyclonal Antibody 基因符号 - BID
UniProt编号 - P70444
产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Store at -20°C. We recommend a brief centrifugation before opening to settle vial contents. Then, apportion into working aliquots and store at -20°C. For shipment or short-term storage (up to one week), 2-8°C is sufficient. 包装信息 数量 100 µL
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