merck millipore,默克密理愽
  • merck millipore,默克密理博,567565,Sodium Stibogluconate - CAS 16037-91-5 - Calbiochem

  • merck millipore,默克密理博,567565,Sodium Stibogluconate - CAS 16037-91-5 - Calbiochem

    产品名称：Sodium Stibogluconate - CAS 16037-91-5 - Calbiochem
    产品型号：567565
    A pentavalent antimony compound that irreversibly inhibits protein tyrosine phosphatase (PTPase) activity, including Src homology PTPase-1 (SHP-1) (99% inhibition at ~11 µM) by forming a stable comple More>>

    merck millipore,默克密理博,567565,Sodium Stibogluconate - CAS 16037-91-5 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,567565,Sodium Stibogluconate - CAS 16037-91-5 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₁₂H₁₇O₁₇Sb₂ · 3Na · 9H₂O16037-91-5
    描述
    概述 A pentavalent antimony compound that irreversibly inhibits protein tyrosine phosphatase (PTPase) activity, including Src homology PTPase-1 (SHP-1) (99% inhibition at ~11 µM) by forming a stable complex. At higher concentrations (~110 µM), it inhibits SHP-2 and PTP1B activities.
    产品目录编号 567565
    品牌系列 Calbiochem®
    同义词 SSG, Antimony Sodium Gluconate, NaSbv, PTP Inhibitor XXIV, SHP1 Inhibitor IV
    参考
    参考 Wortmann, G., et al. 2002. Clin. Infect. Dis. 35, 261.
    Pathak, M.K. and Yi, T. 2001. J. Immunol. 167, 3391.
    产品信息
    CAS号 16037-91-5
    具有ATP竞争性 N
    形式 White solid
    Hill配方 C₁₂H₁₇O₁₇Sb₂ · 3Na · 9H₂O
    化学配方 C₁₂H₁₇O₁₇Sb₂ · 3Na · 9H₂O
    Molar Mass 907.9
    可逆 Y
    结构配方图像
    生物信息
    主靶 PTPase activity, including Src homology PTPase-1 (SHP-1)
    主靶IC50 ~11 µM causing 99% inhibition of protein tyrosine phosphatase (PTPase) activity, including Src homology PTPase-1 (SHP-1)
    纯度 ≥90% by titration on dry basis (≥30% Sb content)
    理化信息
    细胞可渗透 N
    溶解度 H₂O
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 +2°C to +8°C
    避光 Protect from light
    防潮 Protect from moisture
    无需冷冻 No
    特殊指南 Unstable in solution; reconstitute just prior to use.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,567565,Sodium Stibogluconate - CAS 16037-91-5 - Calbiochem

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